C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: basic helix-loop-helix family, member e41
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123095 BHLHE41 9606 - 12:26120026-26125127 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242728 BHLHE41-001 26120026-26125127 protein_coding
  ENST00000394326 BHLHE41-003 26122958-26123768 retained_intron
  ENST00000541271 BHLHE41-002 26123988-26124899 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000242728ENST00000541271
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000242728 4.127±0.00 6.369±0.00 1.131±0.00 18.336±11.88 12.235±7.44 3.033±1.63 3.456±0.00 1.794±1.77 2.037±1.95 3.290±0.25 9.592±0.00 5.755±3.20 4.724±2.42 5.154±1.92
ENST00000541271 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.523±0.00 12.095±0.00 4.526±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004X8 CIL_0004X8_0001 CGP 12:25959029-26125127
CIL_0004X9 CIL_0004X9_0001 CGP 12:26120026-26299290

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001078 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0001191 ISS RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007623 IEA circadian rhythm
GO:0008283 NAS cell proliferation
GO:0009887 NAS organ morphogenesis
GO:0010832 ISS negative regulation of myotube differentiation
GO:0010944 ISS negative regulation of transcription by competitive promoter binding
GO:0030154 NAS cell differentiation
GO:0032922 IEA circadian regulation of gene expression
GO:0042803 ISS protein homodimerization activity
GO:0042826 ISS histone deacetylase binding
GO:0043425 ISS bHLH transcription factor binding
GO:0043426 ISS MRF binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046982 ISS protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0070888 ISS E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041691 bhlhe41 basic helix-loop-helix family, member e41 protein_coding Danio_rerio
ENSMUSG00000030256 Bhlhe41 basic helix-loop-helix family, member e41 protein_coding Mus_musculus

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