C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activin A receptor, type IC
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000335450 ACVR1C-003 ENSG00000123612 9606 - 2:157533742-157628727 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastKidneyLiverLungMuscleENST00000335450
Transcript ID Bladder Breast Kidney Liver Lung Muscle
ENST00000335450 0.169±0.00 0.680±0.00 0.134±0.00 0.225±0.00 0.042±0.00 0.235±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000755 CIL_000755_0001 CGP 2:157414619-157629005
CIL_000752 CIL_000752_0001 CGP 2:157526767-157875862

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004675 IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006468 IC:IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0016361 IDA activin receptor activity, type I
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019838 IPI growth factor binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030154 IDA cell differentiation
GO:0030262 IDA apoptotic nuclear changes
GO:0038092 IMP nodal signaling pathway
GO:0038100 IMP nodal binding
GO:0043280 IMP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046872 IC metal ion binding
GO:0048179 IDA activin receptor complex
GO:1901164 IDA negative regulation of trophoblast cell migration
GO:1901383 IMP negative regulation of chorionic trophoblast cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112608 Acvr1c-003 protein_coding Mus_musculus 0 1491
ENSMUST00000100085 Acvr1c-002 protein_coding Mus_musculus 0 1443
ENSMUST00000028178 Acvr1c-001 protein_coding Mus_musculus 0 1131
ENSMUST00000112607 Acvr1c-004 protein_coding Mus_musculus 0 850
ENSMUST00000154453 Acvr1c-005 protein_coding Mus_musculus 0 311

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