C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: par-6 family cell polarity regulator beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124171 PARD6B 9606 + 20:50731544-50756795 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371610 PARD6B-001 50731544-50753741 protein_coding
  ENST00000396039 PARD6B-002 50731665-50756795 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371610
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371610 0.242±0.00 0.519±0.00 6.942±0.00 0.613±0.03 0.845±0.00 1.135±0.69 0.539±0.01 3.100±1.64 1.250±0.31 3.645±0.52 0.188±0.00 2.408±1.69 1.744±1.02 2.228±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VZ CIL_0007VZ_0001 VISTA 20:50389770-50992625
CIL_000170 CIL_000170_0001 CGP 20:50586108-50756795

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005923 IDA tight junction
GO:0005938 IEA cell cortex
GO:0006461 IDA protein complex assembly
GO:0007043 TAS cell-cell junction assembly
GO:0007049 IEA cell cycle
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007409 TAS axonogenesis
GO:0030334 TAS regulation of cell migration
GO:0034329 TAS cell junction assembly
GO:0043234 IEA protein complex
GO:0045177 IEA apical part of cell
GO:0045216 TAS cell-cell junction organization
GO:0051301 IEA cell division
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 TAS tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003865 pard6b par-6 partitioning defective 6 homolog beta (C. elegans) protein_coding Danio_rerio
ENSMUSG00000044641 Pard6b par-6 family cell polarity regulator beta protein_coding Mus_musculus

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