C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypoxia inducible factor 3, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124440 HIF3A 9606 + 19:46297046-46343433 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000244302 HIF3A-001 46297046-46331513 retained_intron
  ENST00000244303 HIF3A-007 46298390-46339909 protein_coding
  ENST00000291300 HIF3A-009 46298458-46331513 retained_intron
  ENST00000300862 HIF3A-006 46303599-46340100 protein_coding
  ENST00000377670 HIF3A-003 46297046-46343433 protein_coding
  ENST00000472815 HIF3A-004 46298426-46338538 protein_coding
  ENST00000475432 HIF3A-002 46297046-46313363 retained_intron
  ENST00000524533 HIF3A-011 46298298-46304187 retained_intron
  ENST00000525854 HIF3A-013 46305042-46312518 processed_transcript
  ENST00000526506 HIF3A-014 46298433-46308586 nonsense_mediated_decay
  ENST00000528563 HIF3A-018 46298394-46325594 nonsense_mediated_decay
  ENST00000529205 HIF3A-015 46305086-46309196 retained_intron
  ENST00000529542 HIF3A-017 46321780-46331496 retained_intron
  ENST00000531043 HIF3A-016 46309221-46312653 nonsense_mediated_decay
  ENST00000533145 HIF3A-012 46298422-46308683 protein_coding
  ENST00000533789 HIF3A-010 46297046-46309266 nonsense_mediated_decay
  ENST00000600236 HIF3A-008 46320392-46321918 retained_intron
  ENST00000600383 HIF3A-023 46303849-46338538 protein_coding
  ENST00000600879 HIF3A-024 46303849-46308767 nonsense_mediated_decay

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000244303ENST00000377670ENST00000472815ENST00000475432ENST00000525854ENST00000528563ENST00000529542ENST00000600383
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000244303 N/A N/A N/A N/A N/A 0.490±0.00 N/A 1.513±0.00 1.720±0.00 N/A N/A N/A N/A
ENST00000377670 6.417±0.00 3.565±0.00 1.807±0.00 1.861±1.75 3.766±0.00 10.506±0.00 2.849±0.00 0.457±0.00 1.525±0.00 0.433±0.34 0.856±0.95 11.163±4.07 1.300±0.00
ENST00000472815 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.177±0.00 N/A N/A
ENST00000475432 N/A 3.233±0.00 N/A 0.129±0.00 N/A N/A N/A N/A 1.289±0.00 N/A 0.139±0.05 N/A N/A
ENST00000525854 N/A N/A N/A 0.468±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000528563 N/A N/A N/A N/A N/A 0.654±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000529542 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.134±0.00 N/A N/A
ENST00000600383 N/A N/A N/A N/A 14.667±0.00 N/A N/A N/A 5.300±0.00 0.807±0.00 N/A 11.596±3.72 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003714 IDA transcription corepressor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007165 IEA signal transduction
GO:0046983 IEA protein dimerization activity
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041169 hif1al hypoxia-inducible factor 1, alpha subunit, like protein_coding Danio_rerio
ENSMUSG00000004328 Hif3a hypoxia inducible factor 3, alpha subunit protein_coding Mus_musculus

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