C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamic-oxaloacetic transaminase 2, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125166 GOT2 9606 - 16:58707131-58734357 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245206 GOT2-001 58707131-58734357 protein_coding
  ENST00000434819 GOT2-005 58707818-58734326 protein_coding
  ENST00000492378 GOT2-002 58721645-58734335 retained_intron
  ENST00000494627 GOT2-004 58709049-58716383 retained_intron
  ENST00000496461 GOT2-003 58718217-58734302 retained_intron
  ENST00000564400 GOT2-009 58716013-58734342 processed_transcript
  ENST00000568368 GOT2-010 58718570-58734316 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245206ENST00000434819ENST00000564400
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245206 17.748±0.00 25.861±0.00 4.755±0.00 28.383±6.16 8.643±6.00 16.157±7.26 55.980±39.94 22.425±5.44 42.870±37.50 6.700±4.39 52.461±25.67 22.314±11.35 18.174±4.70 23.722±6.89
ENST00000434819 N/A N/A 1.934±0.00 N/A 4.551±0.00 N/A 5.428±0.00 12.370±0.00 N/A N/A N/A 2.713±0.00 N/A N/A
ENST00000564400 N/A N/A N/A N/A 5.850±0.00 N/A 7.168±0.00 N/A N/A 1.698±0.00 N/A 6.844±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004J0 CIL_0004J0_0001 CGP 16:58665109-58734357

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004069 ISS L-aspartate:2-oxoglutarate aminotransferase activity
GO:0005739 ISS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0005886 IDA plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006107 IEA oxaloacetate metabolic process
GO:0006531 ISS aspartate metabolic process
GO:0006532 IEA aspartate biosynthetic process
GO:0006533 IDA aspartate catabolic process
GO:0006536 ISS glutamate metabolic process
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0009058 IEA biosynthetic process
GO:0015908 IEP fatty acid transport
GO:0016212 IEA kynurenine-oxoglutarate transaminase activity
GO:0019470 TAS 4-hydroxyproline catabolic process
GO:0019550 IEA glutamate catabolic process to aspartate
GO:0019551 IEA glutamate catabolic process to 2-oxoglutarate
GO:0030170 IEA pyridoxal phosphate binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045471 IDA response to ethanol
GO:0070062 IDA extracellular vesicular exosome
GO:0080130 IEA L-phenylalanine:2-oxoglutarate aminotransferase activity
GO:0097052 IEA L-kynurenine metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005840 got2b glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2) protein_coding Danio_rerio
ENSDARG00000041068 got2a glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2) protein_coding Danio_rerio
ENSMUSG00000031672 Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial protein_coding Mus_musculus

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