C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin induced gene 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125629 INSIG2 9606 + 2:118088452-118110997 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245787 INSIG2-001 118088474-118110028 protein_coding
  ENST00000411929 INSIG2-007 118088452-118108372 nonsense_mediated_decay
  ENST00000467223 INSIG2-004 118088550-118108390 processed_transcript
  ENST00000471186 INSIG2-003 118088474-118110020 processed_transcript
  ENST00000479999 INSIG2-006 118106659-118108467 processed_transcript
  ENST00000485520 INSIG2-002 118088474-118110997 processed_transcript
  ENST00000488995 INSIG2-005 118102538-118107142 processed_transcript
  ENST00000614681 INSIG2-201 118096418-118108853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245787ENST00000411929ENST00000471186ENST00000485520ENST00000614681
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245787 3.482±0.00 8.609±0.00 2.257±0.00 4.643±0.99 2.478±1.46 3.131±0.89 0.751±0.00 5.614±0.75 2.476±0.60 3.839±0.14 0.644±0.00 5.507±1.16 3.000±0.18 4.768±1.06
ENST00000411929 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.764±0.00 N/A
ENST00000471186 N/A N/A N/A N/A N/A 0.866±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000485520 0.569±0.00 1.881±0.00 N/A 1.035±0.54 0.859±0.00 1.666±0.00 0.579±0.00 1.400±0.00 N/A 1.052±0.00 N/A 1.585±0.00 0.597±0.00 0.756±0.08
ENST00000614681 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.526±0.00 3.755±0.00 1.450±0.00 1.802±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KO CIL_0007KO_0001 UCNEbase 2:118051989-118547477
CIL_0002WX CIL_0002WX_0002 CGP 2:118088452-118847678

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006641 IEA triglyceride metabolic process
GO:0006695 IEA cholesterol biosynthetic process
GO:0006991 IEA response to sterol depletion
GO:0008134 IEA transcription factor binding
GO:0008203 IEA cholesterol metabolic process
GO:0010894 IEA negative regulation of steroid biosynthetic process
GO:0016126 IEA sterol biosynthetic process
GO:0032868 IEA response to insulin
GO:0032933 IDA SREBP signaling pathway
GO:0032937 IDA SREBP-SCAP-Insig complex
GO:0033993 IEA response to lipid
GO:0042472 IEA inner ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0044281 TAS small molecule metabolic process
GO:0045717 IEA negative regulation of fatty acid biosynthetic process
GO:0060021 IEA palate development
GO:0060363 IEA cranial suture morphogenesis
GO:0070542 IEA response to fatty acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037203 insig2 insulin induced gene 2 protein_coding Danio_rerio
ENSMUSG00000003721 Insig2 insulin induced gene 2 protein_coding Mus_musculus

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