C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin induced gene 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000245787 INSIG2-001 ENSG00000125629 9606 + 2:118088474-118110028 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245787
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245787 3.482±0.00 8.609±0.00 2.257±0.00 4.643±0.99 2.478±1.46 3.131±0.89 0.751±0.00 5.614±0.75 2.476±0.60 3.839±0.14 0.644±0.00 5.507±1.16 3.000±0.18 4.768±1.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KO CIL_0007KO_0001 UCNEbase 2:118051989-118547477
CIL_0002WX CIL_0002WX_0002 CGP 2:118088452-118847678

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006641 IEA triglyceride metabolic process
GO:0006695 IEA cholesterol biosynthetic process
GO:0006991 IEA response to sterol depletion
GO:0008134 IEA transcription factor binding
GO:0008203 IEA cholesterol metabolic process
GO:0010894 IEA negative regulation of steroid biosynthetic process
GO:0016126 IEA sterol biosynthetic process
GO:0032868 IEA response to insulin
GO:0032933 IDA SREBP signaling pathway
GO:0032937 IDA SREBP-SCAP-Insig complex
GO:0033993 IEA response to lipid
GO:0042472 IEA inner ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0044281 TAS small molecule metabolic process
GO:0045717 IEA negative regulation of fatty acid biosynthetic process
GO:0060021 IEA palate development
GO:0060363 IEA cranial suture morphogenesis
GO:0070542 IEA response to fatty acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000160968 Insig2-005 protein_coding Mus_musculus 0 878
ENSMUST00000071064 Insig2-001 protein_coding Mus_musculus 0 837
ENSMUST00000003818 Insig2-002 protein_coding Mus_musculus 0 837
ENSMUST00000159085 Insig2-004 protein_coding Mus_musculus 0 815
ENSMUST00000186915 Insig2-014 protein_coding Mus_musculus 0 547
ENSMUST00000162790 Insig2-011 protein_coding Mus_musculus 0 497
ENSMUST00000159192 Insig2-013 retained_intron Mus_musculus 0 468
ENSMUST00000159528 Insig2-003 retained_intron Mus_musculus 0 387
ENSMUST00000162019 Insig2-012 retained_intron Mus_musculus 0 292

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