C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin induced gene 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003721 Insig2 10090 - 1:121304353-121332589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003818 Insig2-002 121304353-121328024 protein_coding
  ENSMUST00000071064 Insig2-001 121305522-121332589 protein_coding
  ENSMUST00000159085 Insig2-004 121305555-121327678 protein_coding
  ENSMUST00000159125 Insig2-010 121319664-121327682 protein_coding
  ENSMUST00000159192 Insig2-013 121306880-121312414 retained_intron
  ENSMUST00000159528 Insig2-003 121305893-121307318 retained_intron
  ENSMUST00000160688 Insig2-007 121305924-121327793 protein_coding
  ENSMUST00000160968 Insig2-005 121305538-121327746 protein_coding
  ENSMUST00000161068 Insig2-006 121319761-121332550 protein_coding
  ENSMUST00000161818 Insig2-009 121319734-121327688 protein_coding
  ENSMUST00000162019 Insig2-012 121311845-121319728 retained_intron
  ENSMUST00000162582 Insig2-008 121306937-121327765 protein_coding
  ENSMUST00000162790 Insig2-011 121307237-121323191 protein_coding
  ENSMUST00000186915 Insig2-014 121305695-121327719 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003818ENSMUST00000159192ENSMUST00000160688
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003818 7.005±3.16 5.399±1.67 6.028±0.80 8.688±4.79 7.907±3.03 7.056±4.05 5.396±0.26 6.179±4.30 5.999±4.83 5.686±0.00 7.845±3.00 2.352±0.62 2.921±0.07 7.327±1.18
ENSMUST00000159192 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.279±0.65 N/A
ENSMUST00000160688 N/A N/A N/A N/A N/A 6.662±0.00 N/A 15.170±0.00 N/A 14.621±0.00 N/A N/A N/A 29.156±3.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KO CIL_0007KO_0002 UCNEbase 1:120886247-121392907

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0006641 IGI triglyceride metabolic process
GO:0006695 IGI cholesterol biosynthetic process
GO:0006991 IDA response to sterol depletion
GO:0008134 IEA transcription factor binding
GO:0008203 IGI cholesterol metabolic process
GO:0010894 IGI negative regulation of steroid biosynthetic process
GO:0016126 IGI sterol biosynthetic process
GO:0032868 IEA response to insulin
GO:0032933 IEA SREBP signaling pathway
GO:0032937 IEA SREBP-SCAP-Insig complex
GO:0033993 IEA response to lipid
GO:0042472 IGI inner ear morphogenesis
GO:0042474 IGI middle ear morphogenesis
GO:0045717 IGI negative regulation of fatty acid biosynthetic process
GO:0060021 IGI palate development
GO:0060363 IGI cranial suture morphogenesis
GO:0070542 IEA response to fatty acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037203 insig2 insulin induced gene 2 protein_coding Danio_rerio
ENSG00000125629 INSIG2 insulin induced gene 2 protein_coding Homo_sapiens

Loading