C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: helicase (DNA) B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127311 HELB 9606 + 12:66302545-66347645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000247815 HELB-001 66302545-66347645 protein_coding
  ENST00000440906 HELB-003 66302579-66338158 nonsense_mediated_decay
  ENST00000536862 HELB-006 66322740-66324519 retained_intron
  ENST00000542394 HELB-002 66302579-66338169 nonsense_mediated_decay
  ENST00000545134 HELB-004 66302580-66343643 nonsense_mediated_decay
  ENST00000545455 HELB-005 66321402-66325078 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000247815ENST00000440906ENST00000545134
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000247815 0.362±0.00 0.630±0.00 0.426±0.00 0.314±0.00 0.455±0.13 0.213±0.00 0.114±0.06 0.437±0.00 0.308±0.00 N/A 0.053±0.00 0.640±0.40 0.153±0.06 0.376±0.00
ENST00000440906 N/A N/A 0.539±0.00 N/A 0.864±0.00 N/A 0.359±0.00 N/A N/A 1.028±0.00 0.275±0.00 N/A N/A N/A
ENST00000545134 N/A N/A N/A N/A 0.747±0.00 N/A N/A N/A 1.292±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005524 IEA ATP binding
GO:0005658 IDA alpha DNA polymerase:primase complex
GO:0006260 IMP DNA replication
GO:0006261 IEA DNA-dependent DNA replication
GO:0006269 IDA DNA replication, synthesis of RNA primer
GO:0017116 IDA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032508 IEA DNA duplex unwinding
GO:0043141 IDA ATP-dependent 5'-3' DNA helicase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053127 helb helicase (DNA) B protein_coding Danio_rerio
ENSMUSG00000020228 Helb helicase (DNA) B protein_coding Mus_musculus

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