C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: helicase (DNA) B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020228 Helb 10090 - 10:120083608-120112987 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020449 Helb-001 120083608-120112987 protein_coding
  ENSMUST00000148241 Helb-003 120084708-120092209 retained_intron
  ENSMUST00000154501 Helb-002 120084770-120112865 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020449ENSMUST00000148241ENSMUST00000154501
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020449 1.580±0.26 0.517±0.16 2.676±0.19 1.126±0.20 1.459±0.54 2.589±0.41 1.801±0.24 1.980±0.65 3.446±2.36 1.030±0.17 1.198±0.24 2.080±1.09 1.199±0.21 0.284±0.07
ENSMUST00000148241 1.014±0.00 2.620±0.39 1.484±0.26 0.987±0.24 2.571±0.58 3.735±0.37 0.961±0.00 1.303±0.27 2.214±1.78 1.979±0.34 0.619±0.00 2.167±0.68 N/A 0.398±0.00
ENSMUST00000154501 N/A 0.574±0.00 N/A 0.504±0.00 N/A N/A N/A N/A N/A N/A 0.223±0.00 1.098±0.52 N/A 0.171±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WI CIL_0006WI_0002 CGP 10:120083608-120202130

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004003 IDA ATP-dependent DNA helicase activity
GO:0005524 IEA ATP binding
GO:0005658 IEA alpha DNA polymerase:primase complex
GO:0006260 IEA DNA replication
GO:0006261 IDA DNA-dependent DNA replication
GO:0006269 TAS DNA replication, synthesis of RNA primer
GO:0017116 IEA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032508 IEA DNA duplex unwinding
GO:0043141 IEA ATP-dependent 5'-3' DNA helicase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053127 helb helicase (DNA) B protein_coding Danio_rerio
ENSG00000127311 HELB helicase (DNA) B protein_coding Homo_sapiens

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