C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: P450 (cytochrome) oxidoreductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127948 POR 9606 + 7:75899200-75986855 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394893 POR-009 75915164-75986855 protein_coding
  ENST00000412064 POR-024 75953989-75986540 nonsense_mediated_decay
  ENST00000412521 POR-002 75915174-75980411 protein_coding
  ENST00000414186 POR-003 75915182-75980488 protein_coding
  ENST00000418341 POR-004 75945322-75954180 protein_coding
  ENST00000421059 POR-019 75915157-75954109 protein_coding
  ENST00000426184 POR-022 75967843-75980439 protein_coding
  ENST00000432753 POR-020 75918644-75980471 protein_coding
  ENST00000439269 POR-015 75981911-75986832 protein_coding
  ENST00000439297 POR-006 75967845-75979537 protein_coding
  ENST00000439963 POR-018 75907576-75981096 protein_coding
  ENST00000447222 POR-014 75954076-75986599 protein_coding
  ENST00000448410 POR-007 75915149-75980738 nonsense_mediated_decay
  ENST00000449920 POR-021 75921161-75954180 protein_coding
  ENST00000453773 POR-017 75899200-75980393 protein_coding
  ENST00000454934 POR-013 75953989-75986854 nonsense_mediated_decay
  ENST00000460892 POR-010 75980932-75983793 retained_intron
  ENST00000461988 POR-001 75915079-75986855 protein_coding
  ENST00000471238 POR-008 75915157-75979786 retained_intron
  ENST00000475509 POR-005 75967845-75980360 processed_transcript
  ENST00000487247 POR-011 75983436-75985307 retained_intron
  ENST00000493973 POR-016 75985570-75986855 retained_intron
  ENST00000495770 POR-023 75983789-75985366 retained_intron
  ENST00000496888 POR-012 75983316-75985745 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394893ENST00000412064ENST00000439269ENST00000454934ENST00000460892ENST00000461988ENST00000493973
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394893 N/A 9.921±0.00 5.255±0.00 1.402±0.00 N/A N/A 9.382±0.00 N/A 3.620±0.00 6.005±0.00 3.760±0.00 N/A N/A
ENST00000412064 14.767±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000439269 N/A N/A N/A 18.773±0.00 8.971±0.00 N/A 32.492±0.00 N/A N/A N/A N/A 13.642±0.00 N/A
ENST00000454934 N/A N/A N/A N/A N/A N/A N/A 53.453±0.00 N/A N/A N/A N/A N/A
ENST00000460892 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 30.263±0.00 N/A
ENST00000461988 12.901±0.00 N/A 9.527±2.84 17.720±16.13 11.718±0.00 6.461±5.11 34.273±11.87 100.408±0.00 N/A 18.939±0.00 31.614±24.81 47.556±26.60 25.814±0.00
ENST00000493973 N/A N/A N/A N/A N/A N/A 65.205±0.00 147.171±0.00 N/A N/A 77.260±0.00 40.172±9.40 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NP CIL_0006NP_0001 CGP 7:75842602-75986855
CIL_0006NS CIL_0006NS_0001 CGP 7:75899200-75994659

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003420 IEA regulation of growth plate cartilage chondrocyte proliferation
GO:0003958 TAS NADPH-hemoprotein reductase activity
GO:0004128 IEA cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0007584 IEA response to nutrient
GO:0008941 IEA nitric oxide dioxygenase activity
GO:0009055 IEA electron carrier activity
GO:0009437 IEA carnitine metabolic process
GO:0009812 IEA flavonoid metabolic process
GO:0010181 IEA FMN binding
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016787 IEA hydrolase activity
GO:0018393 IEA internal peptidyl-lysine acetylation
GO:0019395 IEA fatty acid oxidation
GO:0019899 IEA enzyme binding
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0032770 IDA positive regulation of monooxygenase activity
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043602 IEA nitrate catabolic process
GO:0045542 IEA positive regulation of cholesterol biosynthetic process
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0046210 IEA nitric oxide catabolic process
GO:0047726 IEA iron-cytochrome-c reductase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 TAS:IEA oxidation-reduction process
GO:0060192 IEA negative regulation of lipase activity
GO:0070988 IEA demethylation
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071372 IEA cellular response to follicle-stimulating hormone stimulus
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process
GO:0090181 IEA regulation of cholesterol metabolic process
GO:0090346 IDA cellular organofluorine metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055092 por P450 (cytochrome) oxidoreductase protein_coding Danio_rerio
ENSDARG00000059035 POR (2 of 2) P450 (cytochrome) oxidoreductase protein_coding Danio_rerio
ENSMUSG00000005514 Por P450 (cytochrome) oxidoreductase protein_coding Mus_musculus

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