C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: P450 (cytochrome) oxidoreductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005514 Por 10090 + 5:135670033-135735326 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005651 Por-001 135689036-135735326 protein_coding
  ENSMUST00000122113 Por-002 135689158-135735326 protein_coding
  ENSMUST00000127096 Por-006 135725728-135730241 protein_coding
  ENSMUST00000132084 Por-009 135733181-135734047 retained_intron
  ENSMUST00000147515 Por-008 135716005-135731878 retained_intron
  ENSMUST00000149684 Por-007 135731550-135733915 retained_intron
  ENSMUST00000150058 Por-005 135674581-135684982 processed_transcript
  ENSMUST00000153500 Por-003 135670033-135731661 protein_coding
  ENSMUST00000153515 Por-004 135674585-135731117 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005651ENSMUST00000122113ENSMUST00000149684ENSMUST00000153500
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005651 90.731±26.90 151.633±32.55 59.352±3.01 30.195±11.20 77.422±27.43 60.947±5.12 19.324±5.34 114.714±9.19 67.997±36.47 139.478±12.43 5.972±0.37 64.737±18.92 44.234±9.56 7.256±0.34
ENSMUST00000122113 N/A N/A N/A 6.234±0.00 N/A N/A N/A N/A N/A N/A N/A 17.419±5.02 18.691±6.68 0.467±0.00
ENSMUST00000149684 N/A N/A N/A 31.591±0.00 63.280±0.00 64.243±2.15 7.417±0.00 96.839±0.00 71.557±0.00 N/A N/A 69.976±24.16 63.791±8.84 3.788±0.49
ENSMUST00000153500 N/A N/A N/A 30.442±0.00 N/A N/A N/A N/A N/A N/A N/A 39.292±0.00 38.806±1.86 6.167±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NP CIL_0006NP_0002 CGP 5:135632618-135735326
CIL_0006NS CIL_0006NS_0002 CGP 5:135670033-135744271

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003420 IEA regulation of growth plate cartilage chondrocyte proliferation
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004128 IEA cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IBA cytosol
GO:0007584 IEA response to nutrient
GO:0008941 IEA nitric oxide dioxygenase activity
GO:0009055 IEA electron carrier activity
GO:0009437 IEA carnitine metabolic process
GO:0009812 IEA flavonoid metabolic process
GO:0010181 IEA FMN binding
GO:0016020 IEA membrane
GO:0016491 IMP oxidoreductase activity
GO:0016709 IBA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016787 IEA hydrolase activity
GO:0018393 IEA internal peptidyl-lysine acetylation
GO:0019395 IEA fatty acid oxidation
GO:0019899 IEA enzyme binding
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0032770 IEA positive regulation of monooxygenase activity
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043602 IEA nitrate catabolic process
GO:0045542 IEA positive regulation of cholesterol biosynthetic process
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0046210 IEA nitric oxide catabolic process
GO:0047726 IEA iron-cytochrome-c reductase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process
GO:0060192 IEA negative regulation of lipase activity
GO:0070988 IEA demethylation
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071372 IEA cellular response to follicle-stimulating hormone stimulus
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0090031 IEA positive regulation of steroid hormone biosynthetic process
GO:0090181 IEA regulation of cholesterol metabolic process
GO:0090346 IEA cellular organofluorine metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055092 por P450 (cytochrome) oxidoreductase protein_coding Danio_rerio
ENSDARG00000059035 POR (2 of 2) P450 (cytochrome) oxidoreductase protein_coding Danio_rerio
ENSG00000127948 POR P450 (cytochrome) oxidoreductase protein_coding Homo_sapiens

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