C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128040 SPINK2 9606 - 4:56809860-56821742 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248701 SPINK2-001 56809861-56821742 protein_coding
  ENST00000504762 SPINK2-003 56809872-56821694 protein_coding
  ENST00000506738 SPINK2-002 56809861-56821742 protein_coding
  ENST00000509707 SPINK2-004 56809860-56811796 retained_intron
  ENST00000616980 SPINK2-201 56809862-56821742 protein_coding
  ENST00000618802 SPINK2-202 56809862-56821742 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000248701ENST00000504762ENST00000506738ENST00000509707ENST00000616980ENST00000618802
Transcript ID Adipose Adrenal Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000248701 N/A N/A N/A N/A N/A N/A N/A N/A 0.190±0.00 N/A 98.130±50.98
ENST00000504762 N/A 0.702±0.00 N/A 0.157±0.00 N/A 0.171±0.00 0.072±0.00 N/A N/A N/A 35.507±10.75
ENST00000506738 N/A 0.266±0.00 N/A N/A N/A 0.756±0.00 0.856±0.00 N/A N/A 0.147±0.08 39.110±0.00
ENST00000509707 0.322±0.00 N/A 0.233±0.00 0.366±0.27 0.546±0.00 N/A N/A N/A N/A N/A N/A
ENST00000616980 N/A N/A 0.079±0.00 0.032±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000618802 N/A 0.551±0.00 0.259±0.00 N/A N/A N/A 0.177±0.00 0.112±0.00 0.120±0.00 0.249±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G9 CIL_0008G9_0001 VISTA 4:56396035-56999166
CIL_0001WS CIL_0001WS_0001 CGP 4:56809860-56935844

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 IEA acrosomal vesicle
GO:0002176 IEA male germ cell proliferation
GO:0004866 TAS endopeptidase inhibitor activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005737 IEA cytoplasm
GO:0007283 IEA spermatogenesis
GO:0007286 IEA spermatid development
GO:0008584 IEA male gonad development
GO:0009566 IEA fertilization
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0072520 IEA seminiferous tubule development
GO:1900004 IEA negative regulation of serine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000053030 Spink2 serine peptidase inhibitor, Kazal type 2 protein_coding Mus_musculus

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