C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine peptidase inhibitor, Kazal type 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053030 Spink2 10090 - 5:77205107-77211471 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065216 Spink2-001 77205107-77211471 protein_coding
  ENSMUST00000120429 Spink2-002 77205107-77211438 protein_coding
  ENSMUST00000121825 Spink2-003 77205112-77211205 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065216ENSMUST00000120429ENSMUST00000121825
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065216 1.789±1.24 0.178±0.06 0.543±0.17 0.194±0.09 0.590±0.20 0.112±0.00 0.592±0.24 0.179±0.13 0.098±0.05 1.672±0.62 0.364±0.21 0.344±0.14 1.611±1.39 727.145±324.78
ENSMUST00000120429 N/A N/A N/A 0.038±0.00 0.243±0.07 0.136±0.01 N/A N/A 0.051±0.01 N/A 0.150±0.07 0.408±0.12 N/A N/A
ENSMUST00000121825 N/A N/A N/A N/A N/A 0.388±0.00 N/A N/A N/A N/A N/A 0.813±0.00 1.126±0.68 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G9 CIL_0008G9_0002 VISTA 5:76829880-77430993
CIL_0001WS CIL_0001WS_0002 CGP 5:77205107-77286432

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001669 IDA acrosomal vesicle
GO:0002176 IMP male germ cell proliferation
GO:0003674 ND molecular_function
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005576 IEA extracellular region
GO:0005737 IDA cytoplasm
GO:0006915 IEA apoptotic process
GO:0007283 IMP spermatogenesis
GO:0007286 IMP spermatid development
GO:0008584 IMP male gonad development
GO:0009566 IMP fertilization
GO:0072520 IMP seminiferous tubule development
GO:1900004 IDA negative regulation of serine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128040 SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) protein_coding Homo_sapiens

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