C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoribosyl pyrophosphate amidotransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128059 PPAT 9606 - 4:56393362-56435615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264220 PPAT-001 56393362-56435615 protein_coding
  ENST00000425339 PPAT-002 56393365-56400916 retained_intron
  ENST00000507648 PPAT-003 56401390-56408328 processed_transcript
  ENST00000507724 PPAT-004 56403074-56435496 nonsense_mediated_decay
  ENST00000510643 PPAT-005 56403063-56435508 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264220ENST00000425339ENST00000507648ENST00000507724
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264220 0.818±0.00 2.339±0.00 2.314±0.50 1.084±0.06 0.965±0.11 0.416±0.29 0.807±0.10 1.218±0.08 0.942±0.00 0.553±0.13 2.478±1.08 1.854±0.18 2.914±0.16
ENST00000425339 N/A N/A N/A 0.728±0.00 N/A N/A N/A N/A 0.133±0.00 N/A 0.336±0.00 N/A N/A
ENST00000507648 N/A N/A N/A N/A N/A N/A N/A N/A 0.521±0.00 N/A N/A N/A N/A
ENST00000507724 N/A N/A N/A N/A N/A 0.954±0.00 5.055±0.00 2.906±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025Q CIL_00025Q_0001 CGP 4:56338287-56435615
CIL_0001WN CIL_0001WN_0001 CGP 4:56393362-56461368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0001822 IEA kidney development
GO:0004044 IEA amidophosphoribosyltransferase activity
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 TAS purine nucleotide biosynthetic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0006543 IEA glutamine catabolic process
GO:0007595 IEA lactation
GO:0008152 IEA metabolic process
GO:0009113 IEA purine nucleobase biosynthetic process
GO:0009116 IEA nucleoside metabolic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0019693 IEA ribose phosphate metabolic process
GO:0031100 IEA organ regeneration
GO:0032869 IEA cellular response to insulin stimulus
GO:0035690 IEA cellular response to drug
GO:0042493 IEA response to drug
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051289 IEA protein homotetramerization
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0060135 IEA maternal process involved in female pregnancy

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004517 ppat phosphoribosyl pyrophosphate amidotransferase protein_coding Danio_rerio
ENSMUSG00000029246 Ppat phosphoribosyl pyrophosphate amidotransferase protein_coding Mus_musculus

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