C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box P2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128573 FOXP2 9606 + 7:114086327-114693772 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000350908 FOXP2-001 114415055-114690100 protein_coding
  ENST00000360232 FOXP2-017 114426500-114654143 protein_coding
  ENST00000378237 FOXP2-010 114415319-114645830 protein_coding
  ENST00000390668 FOXP2-016 114426515-114654143 protein_coding
  ENST00000393489 FOXP2-020 114415323-114689957 protein_coding
  ENST00000393491 FOXP2-201 114414997-114693768 protein_coding
  ENST00000393494 FOXP2-014 114414274-114690163 protein_coding
  ENST00000393495 FOXP2-018 114415112-114642585 protein_coding
  ENST00000393498 FOXP2-005 114415058-114690145 protein_coding
  ENST00000403559 FOXP2-202 114414997-114693768 protein_coding
  ENST00000408937 FOXP2-004 114414997-114693772 protein_coding
  ENST00000412402 FOXP2-006 114086327-114690905 nonsense_mediated_decay
  ENST00000440349 FOXP2-002 114086439-114631584 nonsense_mediated_decay
  ENST00000441290 FOXP2-008 114086560-114669984 nonsense_mediated_decay
  ENST00000452963 FOXP2-015 114426502-114630005 protein_coding
  ENST00000459666 FOXP2-009 114415220-114628982 processed_transcript
  ENST00000462331 FOXP2-007 114414997-114499728 protein_coding
  ENST00000495516 FOXP2-011 114088166-114426510 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000350908ENST00000378237ENST00000393489ENST00000393491ENST00000403559ENST00000408937ENST00000440349ENST00000441290
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000350908 N/A N/A N/A N/A 2.230±0.00 N/A N/A 3.003±0.00 N/A N/A N/A N/A N/A
ENST00000378237 N/A N/A N/A N/A N/A N/A 0.710±0.00 N/A 1.060±0.00 N/A N/A N/A N/A
ENST00000393489 N/A N/A N/A N/A N/A 0.109±0.00 N/A N/A N/A N/A N/A 0.219±0.00 1.235±0.00
ENST00000393491 0.071±0.00 0.326±0.00 N/A 0.572±0.00 N/A 0.056±0.02 0.283±0.00 0.595±0.47 N/A 0.626±0.00 0.310±0.18 0.114±0.00 N/A
ENST00000403559 N/A N/A 1.402±0.00 N/A N/A 0.046±0.01 N/A 0.360±0.00 N/A N/A N/A N/A 0.521±0.00
ENST00000408937 N/A N/A N/A N/A 1.447±0.00 0.025±0.00 N/A N/A N/A 0.328±0.00 0.174±0.08 N/A N/A
ENST00000440349 N/A N/A N/A N/A N/A 0.213±0.00 N/A N/A N/A 1.124±0.00 N/A N/A N/A
ENST00000441290 N/A N/A N/A N/A 0.731±0.00 0.038±0.00 N/A 1.000±0.00 0.395±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084L CIL_00084L_0001 VISTA 7:113618068-114219050
CIL_00090T CIL_00090T_0001 VISTA 7:113853490-114454507
CIL_000412 CIL_000412_0001 CGP 7:113876777-114693772
CIL_000411 CIL_000411_0001 CGP 7:114086327-115019916

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007519 IEA skeletal muscle tissue development
GO:0009791 IEA post-embryonic development
GO:0021549 IEA cerebellum development
GO:0021757 IMP caudate nucleus development
GO:0021758 IMP putamen development
GO:0021987 IEP cerebral cortex development
GO:0030324 IEA lung development
GO:0040007 IEA growth
GO:0042297 IEA vocal learning
GO:0042803 IDA protein homodimerization activity
GO:0043010 IEA camera-type eye development
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048286 IEA lung alveolus development
GO:0048745 IEA smooth muscle tissue development
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0060013 IEA righting reflex
GO:0060501 IEA positive regulation of epithelial cell proliferation involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005453 foxp2 forkhead box P2 protein_coding Danio_rerio
ENSMUSG00000029563 Foxp2 forkhead box P2 protein_coding Mus_musculus

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