C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box P2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029563 Foxp2 10090 + 6:14901349-15441977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031545 Foxp2-001 15185506-15441201 protein_coding
  ENSMUST00000115469 Foxp2-017 15196964-15405675 protein_coding
  ENSMUST00000115470 Foxp2-002 15184647-15199344 protein_coding
  ENSMUST00000115472 Foxp2-007 15185506-15438304 protein_coding
  ENSMUST00000115474 Foxp2-006 15185506-15438023 protein_coding
  ENSMUST00000115475 Foxp2-015 15376689-15439048 nonsense_mediated_decay
  ENSMUST00000115477 Foxp2-201 14901349-15441977 protein_coding
  ENSMUST00000118133 Foxp2-013 15185449-15255007 protein_coding
  ENSMUST00000128567 Foxp2-009 14901477-15286770 protein_coding
  ENSMUST00000131414 Foxp2-020 15196951-15405675 protein_coding
  ENSMUST00000137628 Foxp2-018 15185563-15394815 protein_coding
  ENSMUST00000138273 Foxp2-004 14901478-15287752 retained_intron
  ENSMUST00000140557 Foxp2-014 15196951-15379819 protein_coding
  ENSMUST00000151060 Foxp2-005 14901388-15411938 retained_intron
  ENSMUST00000151301 Foxp2-019 15196949-15397843 protein_coding
  ENSMUST00000152563 Foxp2-016 15376689-15378088 nonsense_mediated_decay
  ENSMUST00000154448 Foxp2-012 15185203-15197075 protein_coding
  ENSMUST00000156883 Foxp2-011 14903457-15196959 processed_transcript
  ENSMUST00000159788 Foxp2-021 15254283-15286770 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031545ENSMUST00000115469ENSMUST00000115472ENSMUST00000115474ENSMUST00000115475ENSMUST00000115477ENSMUST00000118133ENSMUST00000137628ENSMUST00000140557ENSMUST00000151060ENSMUST00000154448
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031545 0.123±0.08 N/A 4.102±0.37 6.085±3.35 0.154±0.05 1.266±0.42 0.457±0.14 0.101±0.01 0.257±0.17 0.593±0.16 0.056±0.02 2.393±0.44 0.030±0.02 0.066±0.04
ENSMUST00000115469 0.387±0.00 0.482±0.04 N/A N/A 0.215±0.00 3.101±0.39 N/A 0.254±0.08 0.255±0.09 0.876±0.00 N/A 8.187±1.94 0.110±0.01 0.215±0.07
ENSMUST00000115472 0.272±0.00 0.503±0.10 N/A N/A N/A 1.573±0.37 0.509±0.03 0.147±0.05 0.323±0.17 0.553±0.13 0.069±0.00 2.797±0.80 0.010±0.00 0.109±0.03
ENSMUST00000115474 0.041±0.00 N/A N/A N/A 0.190±0.11 1.552±0.70 0.246±0.00 N/A 0.163±0.00 N/A N/A N/A N/A 0.012±0.00
ENSMUST00000115475 0.068±0.02 0.500±0.00 N/A N/A N/A N/A N/A N/A 0.363±0.00 N/A 0.060±0.00 N/A 0.001±0.00 0.058±0.00
ENSMUST00000115477 0.212±0.00 0.364±0.12 2.541±0.33 4.459±2.39 0.191±0.03 1.390±0.31 0.250±0.00 0.055±0.02 0.102±0.08 0.581±0.12 0.105±0.05 1.747±0.26 0.047±0.03 0.035±0.00
ENSMUST00000118133 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.011±0.00 N/A
ENSMUST00000137628 N/A 1.019±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140557 N/A N/A N/A N/A N/A N/A N/A 0.183±0.03 0.648±0.00 N/A 0.094±0.00 8.314±2.14 N/A N/A
ENSMUST00000151060 N/A N/A N/A N/A N/A N/A N/A 0.140±0.00 N/A N/A N/A N/A N/A 0.038±0.00
ENSMUST00000154448 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.128±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084L CIL_00084L_0002 VISTA 6:14454338-15055302
CIL_00090T CIL_00090T_0002 VISTA 6:14680242-15281244
CIL_000412 CIL_000412_0002 CGP 6:14713822-15441977
CIL_00095R CIL_00095R_0002 VISTA 6:14882427-15483744
CIL_0007XX CIL_0007XX_0002 VISTA 6:14885821-15487224
CIL_00092C CIL_00092C_0002 VISTA 6:14887323-15489118
CIL_00092B CIL_00092B_0002 VISTA 6:14892947-15494270
CIL_00082W CIL_00082W_0002 VISTA 6:14901156-15503663
CIL_000411 CIL_000411_0002 CGP 6:14901349-15802169

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0002053 IGI positive regulation of mesenchymal cell proliferation
GO:0003677 IDA:ISS DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007519 IGI skeletal muscle tissue development
GO:0009791 IMP post-embryonic development
GO:0021549 IMP cerebellum development
GO:0021757 ISS caudate nucleus development
GO:0021758 ISS putamen development
GO:0021987 IEA cerebral cortex development
GO:0030324 IGI lung development
GO:0040007 IMP growth
GO:0042297 IMP vocal learning
GO:0042803 IPI:ISS protein homodimerization activity
GO:0043010 IMP camera-type eye development
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0048286 IMP lung alveolus development
GO:0048745 IGI smooth muscle tissue development
GO:0050679 IGI positive regulation of epithelial cell proliferation
GO:0060013 IMP righting reflex
GO:0060501 IGI positive regulation of epithelial cell proliferation involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005453 foxp2 forkhead box P2 protein_coding Danio_rerio
ENSG00000128573 FOXP2 forkhead box P2 protein_coding Homo_sapiens

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