C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinetochore-localized astrin/SPAG5 binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128944 KNSTRN 9606 + 15:40382721-40394246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000249776 KNSTRN-001 40382721-40394245 protein_coding
  ENST00000416151 KNSTRN-005 40382721-40394154 protein_coding
  ENST00000448395 KNSTRN-003 40382836-40394172 protein_coding
  ENST00000557920 KNSTRN-011 40382996-40389929 protein_coding
  ENST00000559083 KNSTRN-014 40383255-40392023 nonsense_mediated_decay
  ENST00000559304 KNSTRN-013 40382980-40393618 nonsense_mediated_decay
  ENST00000559591 KNSTRN-008 40382941-40384922 retained_intron
  ENST00000559604 KNSTRN-006 40382721-40383438 retained_intron
  ENST00000560220 KNSTRN-007 40382976-40393626 nonsense_mediated_decay
  ENST00000560321 KNSTRN-015 40382939-40393677 nonsense_mediated_decay
  ENST00000560673 KNSTRN-010 40383004-40386848 retained_intron
  ENST00000560981 KNSTRN-002 40382721-40394172 nonsense_mediated_decay
  ENST00000561169 KNSTRN-004 40382979-40394160 nonsense_mediated_decay
  ENST00000561196 KNSTRN-009 40382976-40384676 retained_intron
  ENST00000561367 KNSTRN-012 40389808-40392000 retained_intron
  ENST00000608100 KNSTRN-016 40382941-40394246 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000448395ENST00000559083ENST00000559304ENST00000559591ENST00000559604ENST00000560220ENST00000560321ENST00000560981ENST00000561169ENST00000561367ENST00000608100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000448395 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.662±0.00 N/A N/A N/A
ENST00000559083 N/A N/A N/A N/A N/A N/A 1.292±0.00 N/A N/A N/A N/A 27.258±0.00 14.327±0.00 98.485±0.00
ENST00000559304 N/A N/A 0.747±0.00 N/A N/A N/A 0.353±0.00 0.810±0.00 N/A N/A 1.141±0.00 N/A N/A N/A
ENST00000559591 N/A N/A N/A N/A N/A N/A N/A 1.287±0.00 N/A N/A N/A N/A N/A N/A
ENST00000559604 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.601±0.00 N/A N/A N/A
ENST00000560220 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.302±0.00 N/A 5.501±0.00 1.827±0.00 16.403±0.00
ENST00000560321 N/A N/A N/A N/A N/A N/A N/A N/A 0.437±0.00 N/A N/A N/A N/A N/A
ENST00000560981 N/A N/A N/A N/A N/A N/A N/A 0.585±0.00 0.730±0.00 0.822±0.45 2.054±0.00 1.588±1.44 1.692±0.00 15.548±6.74
ENST00000561169 N/A N/A N/A 0.976±0.00 N/A N/A N/A N/A 2.777±0.00 0.830±0.00 0.648±0.00 N/A N/A 5.865±0.00
ENST00000561367 N/A N/A N/A N/A N/A N/A N/A N/A 1.104±0.00 N/A N/A N/A N/A N/A
ENST00000608100 1.976±0.00 3.446±0.00 0.317±0.00 2.387±0.74 1.906±1.17 3.562±1.06 1.611±1.18 1.640±1.19 N/A 1.519±0.00 N/A 4.080±1.47 4.629±2.21 17.666±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0001 VISTA 15:39791359-40393937
CIL_00070L CIL_00070L_0001 CGP 15:40358235-40394246
CIL_00070I CIL_00070I_0001 CGP 15:40382721-40435947

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IMP mitotic sister chromatid segregation
GO:0000776 IDA kinetochore
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007051 IMP spindle organization
GO:0007059 IMP chromosome segregation
GO:0015630 IDA microtubule cytoskeleton
GO:0035371 IDA microtubule plus-end
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0072686 IDA mitotic spindle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027331 Knstrn kinetochore-localized astrin/SPAG5 binding protein_coding Mus_musculus

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