C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinetochore-localized astrin/SPAG5 binding
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027331 Knstrn 10090 + 2:118814003-118853957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028803 Knstrn-002 118814254-118834642 protein_coding
  ENSMUST00000110842 Knstrn-004 118814233-118834158 protein_coding
  ENSMUST00000123104 Knstrn-006 118814296-118834068 nonsense_mediated_decay
  ENSMUST00000126045 Knstrn-005 118814277-118830969 protein_coding
  ENSMUST00000134579 Knstrn-003 118814232-118834249 nonsense_mediated_decay
  ENSMUST00000134661 Knstrn-001 118814003-118837696 protein_coding
  ENSMUST00000148877 Knstrn-007 118834075-118853957 nonsense_mediated_decay
  ENSMUST00000176463 Knstrn-009 118831583-118837143 nonsense_mediated_decay
  ENSMUST00000177103 Knstrn-008 118814232-118834181 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028803ENSMUST00000110842ENSMUST00000126045ENSMUST00000134579ENSMUST00000134661ENSMUST00000148877ENSMUST00000177103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028803 0.698±0.34 0.497±0.00 0.773±0.02 3.406±2.78 0.530±0.21 2.543±0.00 0.095±0.00 N/A 11.387±8.28 N/A 0.060±0.04 4.183±3.74 12.084±11.16 35.735±15.23
ENSMUST00000110842 N/A N/A 0.855±0.00 0.233±0.00 0.728±0.00 N/A N/A N/A 18.814±0.10 N/A N/A N/A 8.045±3.57 70.929±0.00
ENSMUST00000126045 N/A N/A N/A N/A N/A N/A N/A 0.354±0.00 N/A N/A N/A N/A 38.978±0.00 271.901±0.00
ENSMUST00000134579 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.096±0.00 7.593±0.34 12.243±0.00 N/A
ENSMUST00000134661 0.777±0.63 0.505±0.18 0.454±0.01 1.930±0.20 0.520±0.06 2.546±0.34 0.130±0.00 0.178±0.07 3.104±3.25 0.586±0.08 0.031±0.01 2.301±0.81 2.014±1.08 4.586±3.20
ENSMUST00000148877 N/A N/A N/A N/A N/A N/A N/A N/A 0.181±0.00 N/A N/A N/A N/A N/A
ENSMUST00000177103 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.103±0.05 24.679±0.00 26.518±24.41 240.079±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0002 VISTA 2:118232227-118834856
CIL_00070L CIL_00070L_0002 CGP 2:118779719-118853957
CIL_00070I CIL_00070I_0002 CGP 2:118814003-118882909

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 ISS mitotic sister chromatid segregation
GO:0000776 ISS kinetochore
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007051 ISS spindle organization
GO:0007059 ISS chromosome segregation
GO:0015630 IEA microtubule cytoskeleton
GO:0035371 ISS microtubule plus-end
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0072686 ISS mitotic spindle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128944 KNSTRN kinetochore-localized astrin/SPAG5 binding protein protein_coding Homo_sapiens

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