C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipopolysaccharide binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129988 LBP 9606 + 20:38346356-38377023 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217407 LBP-001 38346356-38377023 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217407 2.330±0.00 10.809±0.00 0.408±0.00 0.103±0.00 1.377±0.85 3.312±0.00 0.342±0.00 23.578±10.01 983.709±0.00 0.065±0.00 0.873±0.80 0.211±0.14 0.226±0.10 0.477±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081Y CIL_00081Y_0001 VISTA 20:38219747-38821106
CIL_0004O1 CIL_0004O1_0001 CGP 20:38260149-38377023

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001530 IDA lipopolysaccharide binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002232 IEA leukocyte chemotaxis involved in inflammatory response
GO:0002281 ISS macrophage activation involved in immune response
GO:0005102 ISS receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0006953 IEP acute-phase response
GO:0006968 ISS cellular defense response
GO:0008228 IC opsonization
GO:0008289 IEA lipid binding
GO:0009986 IDA cell surface
GO:0015920 IDA lipopolysaccharide transport
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032490 IDA detection of molecule of bacterial origin
GO:0032496 IDA response to lipopolysaccharide
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0032722 IEA positive regulation of chemokine production
GO:0032755 IDA positive regulation of interleukin-6 production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034145 IDA positive regulation of toll-like receptor 4 signaling pathway
GO:0042535 IEA positive regulation of tumor necrosis factor biosynthetic process
GO:0043032 IDA positive regulation of macrophage activation
GO:0044130 IEA negative regulation of growth of symbiont in host
GO:0045087 IC innate immune response
GO:0050829 IDA defense response to Gram-negative bacterium
GO:0050830 IDA defense response to Gram-positive bacterium
GO:0060265 ISS positive regulation of respiratory burst involved in inflammatory response
GO:0070062 IDA extracellular vesicular exosome
GO:0070891 IDA lipoteichoic acid binding
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071223 IDA cellular response to lipoteichoic acid
GO:0090023 IEA positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000016024 Lbp lipopolysaccharide binding protein protein_coding Mus_musculus

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