C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipopolysaccharide binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016024 Lbp 10090 + 2:158306493-158332852 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016168 Lbp-001 158306493-158332852 protein_coding
  ENSMUST00000109491 Lbp-002 158306493-158310506 protein_coding
  ENSMUST00000129811 Lbp-003 158314206-158324642 protein_coding
  ENSMUST00000146600 Lbp-004 158306612-158318613 retained_intron
  ENSMUST00000152541 Lbp-005 158306493-158320956 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000016168ENSMUST00000129811ENSMUST00000146600ENSMUST00000152541
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000016168 65.552±24.57 5.829±0.55 17.572±3.23 0.434±0.12 11.088±2.04 2.368±0.93 2.428±0.44 2.994±0.44 29.621±15.14 22.122±5.75 1.987±0.31 40.602±17.56 7.295±3.07 1.630±0.78
ENSMUST00000129811 N/A N/A N/A N/A 51.630±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.891±0.00
ENSMUST00000146600 N/A N/A N/A 0.033±0.00 N/A 1.075±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000152541 N/A 4.379±0.00 N/A N/A N/A 1.227±0.16 N/A N/A N/A 8.854±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081Y CIL_00081Y_0002 VISTA 2:158139041-158740388
CIL_0004O1 CIL_0004O1_0002 CGP 2:158258094-158332852

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IDA lipopolysaccharide binding
GO:0002232 IMP leukocyte chemotaxis involved in inflammatory response
GO:0002281 IDA macrophage activation involved in immune response
GO:0005102 IDA receptor binding
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0006953 IMP acute-phase response
GO:0008228 IC opsonization
GO:0009986 IDA cell surface
GO:0015920 IEA lipopolysaccharide transport
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032490 IEA detection of molecule of bacterial origin
GO:0032496 IMP response to lipopolysaccharide
GO:0032720 IEA negative regulation of tumor necrosis factor production
GO:0032722 IMP positive regulation of chemokine production
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0034145 IEA positive regulation of toll-like receptor 4 signaling pathway
GO:0042535 IMP positive regulation of tumor necrosis factor biosynthetic process
GO:0043032 IEA positive regulation of macrophage activation
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0045087 IMP innate immune response
GO:0050829 IMP defense response to Gram-negative bacterium
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0060265 IMP positive regulation of respiratory burst involved in inflammatory response
GO:0070062 IEA extracellular vesicular exosome
GO:0070891 IEA lipoteichoic acid binding
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071223 IEA cellular response to lipoteichoic acid
GO:0090023 IMP positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000129988 LBP lipopolysaccharide binding protein protein_coding Homo_sapiens

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