C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ECSIT signalling integrator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130159 ECSIT 9606 - 19:11505916-11529174 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252440 ECSIT-004 11505929-11529137 protein_coding
  ENST00000270517 ECSIT-001 11505916-11529174 protein_coding
  ENST00000417981 ECSIT-005 11506002-11529172 protein_coding
  ENST00000585318 ECSIT-002 11507490-11529132 protein_coding
  ENST00000585898 ECSIT-013 11506075-11507709 retained_intron
  ENST00000586149 ECSIT-014 11519097-11529099 protein_coding
  ENST00000588998 ECSIT-008 11505929-11529096 protein_coding
  ENST00000590480 ECSIT-006 11513111-11529130 protein_coding
  ENST00000591104 ECSIT-003 11506184-11528865 protein_coding
  ENST00000591352 ECSIT-012 11507772-11513858 processed_transcript
  ENST00000592312 ECSIT-007 11506301-11529124 protein_coding
  ENST00000592571 ECSIT-010 11505958-11513168 nonsense_mediated_decay
  ENST00000592665 ECSIT-009 11513139-11528827 protein_coding
  ENST00000593231 ECSIT-011 11507700-11513970 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252440ENST00000270517ENST00000417981ENST00000585318ENST00000585898ENST00000588998ENST00000590480ENST00000591104ENST00000592312ENST00000592571
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252440 6.838±0.00 N/A N/A N/A 6.753±0.00 11.087±0.00 12.631±0.00 N/A N/A N/A 16.274±0.00 N/A N/A N/A
ENST00000270517 5.626±0.00 10.966±0.00 1.452±0.00 8.027±0.00 5.690±4.18 15.859±0.00 18.072±13.43 15.230±0.00 7.584±6.01 0.312±0.00 15.471±13.25 26.190±13.17 11.767±3.41 16.218±7.97
ENST00000417981 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.079±2.45 N/A
ENST00000585318 10.334±0.00 N/A N/A N/A N/A 7.864±5.10 2.229±0.00 4.162±0.00 1.070±0.00 12.524±0.00 12.117±1.16 N/A N/A N/A
ENST00000585898 10.424±0.00 N/A N/A N/A 6.807±5.57 20.930±0.00 N/A 3.875±0.00 1.806±0.00 N/A N/A N/A N/A 48.906±0.00
ENST00000588998 N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.758±0.00 N/A N/A N/A N/A
ENST00000590480 7.367±0.00 11.509±0.00 N/A N/A 9.101±0.00 N/A N/A 14.235±0.00 N/A N/A N/A N/A N/A N/A
ENST00000591104 N/A N/A N/A N/A 0.534±0.00 1.252±0.00 N/A N/A 1.030±0.00 N/A 6.388±0.00 0.839±0.00 N/A N/A
ENST00000592312 N/A N/A 1.883±0.00 N/A N/A N/A N/A N/A N/A 0.405±0.00 N/A N/A N/A N/A
ENST00000592571 N/A 8.818±0.00 1.454±0.00 N/A N/A 1.408±0.00 17.170±0.00 11.694±5.14 12.329±0.00 8.288±5.88 10.011±0.00 11.783±6.04 N/A 13.090±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000764 CIL_000764_0001 CGP 19:11483427-11529174
CIL_000767 CIL_000767_0001 CGP 19:11505916-11550323

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001707 IEA mesoderm formation
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016651 IDA oxidoreductase activity, acting on NAD(P)H
GO:0030509 IEA BMP signaling pathway
GO:0045087 IEA innate immune response
GO:0051341 IDA regulation of oxidoreductase activity
GO:0055114 IDA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062834 ecsit ECSIT homolog (Drosophila) protein_coding Danio_rerio
ENSMUSG00000066839 Ecsit ECSIT homolog (Drosophila) protein_coding Mus_musculus

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