C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily M, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130529 TRPM4 9606 + 19:49157741-49211836 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252826 TRPM4-001 49157741-49211836 protein_coding
  ENST00000427978 TRPM4-006 49157815-49211680 protein_coding
  ENST00000594568 TRPM4-010 49167644-49168337 retained_intron
  ENST00000595071 TRPM4-008 49182526-49211836 retained_intron
  ENST00000595519 TRPM4-003 49157792-49211836 nonsense_mediated_decay
  ENST00000595882 TRPM4-012 49188868-49196716 retained_intron
  ENST00000596338 TRPM4-007 49157832-49211749 retained_intron
  ENST00000597316 TRPM4-013 49210734-49211834 protein_coding
  ENST00000598502 TRPM4-005 49157832-49211749 nonsense_mediated_decay
  ENST00000598691 TRPM4-009 49157741-49171373 protein_coding
  ENST00000598697 TRPM4-004 49157766-49211834 nonsense_mediated_decay
  ENST00000599459 TRPM4-014 49210601-49211400 retained_intron
  ENST00000599628 TRPM4-002 49157792-49159921 protein_coding
  ENST00000601347 TRPM4-011 49168627-49182755 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252826ENST00000427978ENST00000595071ENST00000595519ENST00000595882ENST00000596338ENST00000597316ENST00000598502ENST00000598691ENST00000598697ENST00000599459ENST00000599628ENST00000601347
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252826 6.266±0.00 2.438±0.00 0.447±0.00 0.703±0.00 5.122±2.82 N/A N/A 9.006±0.00 0.504±0.00 6.600±0.00 0.726±0.00 2.124±0.00 7.182±2.20 1.491±0.00
ENST00000427978 N/A N/A 1.418±0.00 0.993±0.00 1.301±0.00 3.213±0.00 0.391±0.00 0.228±0.00 N/A N/A N/A 1.041±0.21 1.424±0.00 2.380±0.00
ENST00000595071 N/A N/A 0.546±0.00 N/A N/A N/A N/A N/A 0.732±0.07 N/A N/A 0.488±0.00 N/A 2.049±0.00
ENST00000595519 N/A N/A N/A N/A N/A 2.008±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000595882 N/A N/A N/A N/A N/A N/A N/A 1.653±0.00 N/A N/A N/A N/A N/A N/A
ENST00000596338 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.507±0.00 N/A 1.351±0.00 N/A N/A
ENST00000597316 N/A N/A N/A N/A N/A N/A N/A N/A 6.033±0.00 N/A N/A N/A N/A N/A
ENST00000598502 1.851±0.00 3.335±0.00 N/A N/A N/A N/A 0.703±0.00 N/A N/A 0.446±0.00 N/A 0.942±0.00 N/A N/A
ENST00000598691 N/A N/A N/A N/A N/A N/A 0.513±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000598697 N/A N/A N/A 0.856±0.00 2.549±0.00 4.282±0.00 0.426±0.18 N/A 0.533±0.00 N/A N/A 2.674±0.00 N/A 1.631±0.00
ENST00000599459 N/A N/A N/A N/A N/A N/A N/A N/A 3.253±0.00 N/A N/A N/A N/A N/A
ENST00000599628 N/A 1.866±0.00 N/A 0.496±0.00 N/A N/A 1.027±0.70 3.061±2.67 0.904±0.00 1.120±0.00 1.269±0.00 0.347±0.00 N/A N/A
ENST00000601347 N/A N/A 3.384±0.00 N/A N/A 19.867±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003AT CIL_0003AT_0002 CGP 19:49151198-49211836

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002407 ISS dendritic cell chemotaxis
GO:0002724 IDA regulation of T cell cytokine production
GO:0005216 IEA ion channel activity
GO:0005227 ISS calcium activated cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006811 IEA ion transport
GO:0006816 IEA calcium ion transport
GO:0008284 IDA positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016925 IDA protein sumoylation
GO:0034220 TAS ion transmembrane transport
GO:0042310 IEA vasoconstriction
GO:0042391 IEA regulation of membrane potential
GO:0055085 TAS:IEA transmembrane transport
GO:0061337 IEA cardiac conduction
GO:0070588 TAS calcium ion transmembrane transport
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059993 trpm4a transient receptor potential cation channel, subfamily M, member 4a protein_coding Danio_rerio
ENSDARG00000063347 TRPM4 (2 of 3) transient receptor potential cation channel, subfamily M, member 4 protein_coding Danio_rerio
ENSDARG00000063435 TRPM4 (3 of 3) transient receptor potential cation channel, subfamily M, member 4 protein_coding Danio_rerio
ENSMUSG00000038260 Trpm4 transient receptor potential cation channel, subfamily M, member 4 protein_coding Mus_musculus

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