C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2M
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130725 UBE2M 9606 - 19:58555712-58558960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253023 UBE2M-001 58555712-58558960 protein_coding
  ENST00000593801 UBE2M-004 58556594-58557149 retained_intron
  ENST00000595957 UBE2M-006 58556141-58558954 protein_coding
  ENST00000596985 UBE2M-005 58556201-58557089 protein_coding
  ENST00000599829 UBE2M-003 58556582-58557129 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253023ENST00000593801ENST00000595957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253023 44.821±0.00 38.302±0.00 0.516±0.00 51.250±46.09 21.475±20.08 23.458±21.43 20.531±18.98 18.728±18.38 10.992±8.31 22.882±22.46 35.233±34.03 32.766±20.55 56.293±2.67 59.129±4.17
ENST00000593801 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.491±0.00 N/A N/A N/A N/A
ENST00000595957 N/A N/A 2.686±0.00 2.595±0.00 0.681±0.00 0.808±0.00 23.736±0.00 6.749±3.73 4.528±0.00 19.298±0.00 26.705±0.00 9.416±0.00 13.165±0.73 15.086±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070T CIL_00070T_0001 CGP 19:58551566-58558960
CIL_0003CJ CIL_0003CJ_0001 CGP 19:58555712-58573575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IMP ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006464 IMP cellular protein modification process
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0016567 IMP protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0018169 IDA ribosomal S6-glutamic acid ligase activity
GO:0019788 IDA NEDD8 ligase activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045116 IEA protein neddylation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000005575 Ube2m ubiquitin-conjugating enzyme E2M protein_coding Mus_musculus

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