C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy related 4D, cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130734 ATG4D 9606 + 19:10543895-10553418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309469 ATG4D-001 10543918-10553418 protein_coding
  ENST00000585437 ATG4D-011 10551936-10553144 protein_coding
  ENST00000585752 ATG4D-012 10543918-10552324 nonsense_mediated_decay
  ENST00000586417 ATG4D-002 10543895-10553124 nonsense_mediated_decay
  ENST00000586477 ATG4D-007 10544283-10547075 protein_coding
  ENST00000586863 ATG4D-008 10544309-10552019 protein_coding
  ENST00000587256 ATG4D-009 10545120-10552121 protein_coding
  ENST00000588667 ATG4D-005 10543971-10553418 nonsense_mediated_decay
  ENST00000588857 ATG4D-003 10543917-10553067 nonsense_mediated_decay
  ENST00000588972 ATG4D-010 10549029-10553165 protein_coding
  ENST00000589753 ATG4D-006 10545010-10553418 nonsense_mediated_decay
  ENST00000590096 ATG4D-004 10543917-10549034 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungMusclePlacentaTestisENST00000585752ENST00000586417ENST00000588857
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Muscle Placenta Testis
ENST00000585752 N/A N/A N/A 0.609±0.00 N/A N/A N/A N/A N/A N/A
ENST00000586417 2.833±2.38 N/A 4.652±3.58 4.410±3.74 4.384±3.01 N/A 9.840±0.00 7.607±5.14 6.608±0.00 19.266±0.00
ENST00000588857 N/A 6.378±0.00 N/A 9.692±0.00 11.512±0.00 2.980±0.00 N/A 12.890±0.00 6.271±0.06 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002SU CIL_0002SU_0001 CGP 19:10512742-10553418
CIL_000496 CIL_000496_0001 CGP 19:10543895-10566037

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 ISS cysteine-type endopeptidase activity
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0006508 IEA proteolysis
GO:0006914 IEA autophagy
GO:0006915 IEA apoptotic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0015031 IEA protein transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043548 atg4da autophagy related 4D, cysteine peptidase a protein_coding Danio_rerio
ENSDARG00000088145 atg4db autophagy related 4D, cysteine peptidase b protein_coding Danio_rerio
ENSMUSG00000002820 Atg4d autophagy related 4D, cysteine peptidase protein_coding Mus_musculus

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