C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: A kinase (PRKA) anchor protein 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131016 AKAP12 9606 + 6:151239999-151358557 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253332 AKAP12-001 151240374-151356773 protein_coding
  ENST00000354675 AKAP12-002 151325688-151356773 protein_coding
  ENST00000359755 AKAP12-201 151341686-151356773 protein_coding
  ENST00000402676 AKAP12-202 151239999-151358557 protein_coding
  ENST00000490177 AKAP12-003 151341702-151349186 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253332ENST00000354675ENST00000359755ENST00000402676
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253332 13.113±0.00 N/A 3.360±0.00 4.257±1.67 8.226±0.43 8.499±3.55 1.233±0.45 2.888±0.00 6.218±5.55 19.630±13.98 0.280±0.00 2.561±1.23 5.799±2.89 37.379±0.00
ENST00000354675 26.197±0.00 3.407±0.00 N/A N/A 1.923±0.00 14.595±11.10 0.772±0.34 0.834±0.00 1.521±0.00 1.376±0.00 1.199±0.00 5.746±3.10 5.057±0.00 N/A
ENST00000359755 10.391±0.00 4.194±0.00 N/A 9.292±0.00 14.457±0.00 14.054±0.00 1.978±0.00 5.319±0.00 N/A N/A 0.824±0.00 9.690±9.27 N/A 30.757±0.00
ENST00000402676 N/A N/A 1.738±0.00 3.571±0.93 4.396±0.00 N/A 0.974±0.33 0.832±0.00 7.443±0.00 2.781±0.00 N/A 7.101±3.16 3.174±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EE CIL_0005EE_0001 CGP 6:150865549-151358557
CIL_00030I CIL_00030I_0002 CGP 6:151239999-151391548

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006605 IEA protein targeting
GO:0007165 IEA signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0008179 IPI adenylate cyclase binding
GO:0010739 IMP positive regulation of protein kinase A signaling
GO:0030819 IMP positive regulation of cAMP biosynthetic process
GO:0051018 IEA protein kinase A binding
GO:0090036 IEA regulation of protein kinase C signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055678 akap12b A kinase (PRKA) anchor protein (gravin) 12b protein_coding Danio_rerio
ENSDARG00000091792 akap12a A kinase (PRKA) anchor protein (gravin) 12a protein_coding Danio_rerio
ENSMUSG00000038587 Akap12 A kinase (PRKA) anchor protein (gravin) 12 protein_coding Mus_musculus

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