C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: A kinase (PRKA) anchor protein (gravin) 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038587 Akap12 10090 + 10:4266329-4359468 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045730 Akap12-201 4266329-4359468 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045730 6.497±2.84 1.972±0.24 28.954±16.73 9.688±3.87 4.155±1.11 3.008±0.35 3.262±1.74 2.403±0.85 0.655±0.53 11.498±3.51 0.765±0.57 5.126±1.47 2.628±1.34 118.011±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EE CIL_0005EE_0002 CGP 10:3973118-4359468
CIL_00030I CIL_00030I_0003 CGP 10:4266329-4388108

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005925 IEA focal adhesion
GO:0006605 IEA protein targeting
GO:0007165 TAS signal transduction
GO:0008179 IEA adenylate cyclase binding
GO:0010739 IEA positive regulation of protein kinase A signaling
GO:0030159 TAS receptor signaling complex scaffold activity
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0051018 IEA protein kinase A binding
GO:0090036 IEA regulation of protein kinase C signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055678 akap12b A kinase (PRKA) anchor protein (gravin) 12b protein_coding Danio_rerio
ENSDARG00000091792 akap12a A kinase (PRKA) anchor protein (gravin) 12a protein_coding Danio_rerio
ENSG00000131016 AKAP12 A kinase (PRKA) anchor protein 12 protein_coding Homo_sapiens

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