C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome c oxidase subunit IV isoform 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131143 COX4I1 9606 + 16:85798633-85807044 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253452 COX4I1-001 85799684-85807002 protein_coding
  ENST00000561569 COX4I1-009 85799697-85807002 protein_coding
  ENST00000562336 COX4I1-016 85799693-85807044 protein_coding
  ENST00000562929 COX4I1-017 85805069-85807031 processed_transcript
  ENST00000563774 COX4I1-008 85799696-85805350 retained_intron
  ENST00000564544 COX4I1-015 85799708-85806975 nonsense_mediated_decay
  ENST00000564648 COX4I1-005 85801202-85806967 retained_intron
  ENST00000564903 COX4I1-004 85801202-85806968 protein_coding
  ENST00000565078 COX4I1-006 85798633-85804992 protein_coding
  ENST00000566115 COX4I1-010 85799638-85805096 nonsense_mediated_decay
  ENST00000566405 COX4I1-013 85799698-85806802 protein_coding
  ENST00000566617 COX4I1-007 85799760-85805309 retained_intron
  ENST00000567241 COX4I1-012 85799654-85805328 retained_intron
  ENST00000567266 COX4I1-019 85799697-85805426 retained_intron
  ENST00000568339 COX4I1-003 85799622-85807002 retained_intron
  ENST00000568794 COX4I1-011 85799683-85806805 protein_coding
  ENST00000569997 COX4I1-002 85803057-85807002 retained_intron
  ENST00000570123 COX4I1-014 85799612-85805742 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253452ENST00000562336ENST00000562929ENST00000566405ENST00000570123
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253452 175.899±0.00 362.417±0.00 20.510±0.00 180.707±86.54 147.899±131.19 194.505±121.56 371.791±340.21 218.053±174.80 154.159±116.66 188.374±156.78 188.600±123.24 309.037±169.02 489.141±91.18 253.512±18.92
ENST00000562336 N/A N/A N/A 27.970±0.00 4.886±0.00 N/A 17.716±0.00 13.174±0.00 N/A N/A 28.923±0.00 4.891±0.00 N/A N/A
ENST00000562929 N/A N/A N/A N/A N/A N/A N/A N/A 22.523±0.00 N/A N/A 195.707±0.00 196.868±61.34 107.014±0.00
ENST00000566405 73.303±0.00 N/A 14.211±0.00 156.677±0.00 53.598±42.80 N/A 19.493±0.00 N/A N/A N/A N/A 13.146±0.00 N/A N/A
ENST00000570123 N/A N/A N/A N/A N/A N/A 22.384±0.00 N/A N/A N/A 45.517±0.00 12.235±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HH CIL_0008HH_0001 VISTA 16:85286489-85888130
CIL_00079A CIL_00079A_0001 CGP 16:85690084-85799608
CIL_00049A CIL_00049A_0002 CGP 16:85771758-85807044
CIL_0000IY CIL_0000IY_0001 CGP 16:85798633-85922609

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004129 IEA cytochrome-c oxidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006091 TAS generation of precursor metabolites and energy
GO:0007584 IEA response to nutrient
GO:0016020 IDA membrane
GO:0022904 TAS respiratory electron transport chain
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032970 cox4i1 cytochrome c oxidase subunit IV isoform 1 protein_coding Danio_rerio
ENSMUSG00000031818 Cox4i1 cytochrome c oxidase subunit IV isoform 1 protein_coding Mus_musculus

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