C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: coagulation factor XII (Hageman factor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000253496 F12-001 ENSG00000131187 9606 - 5:177402140-177409576 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverENST00000253496
Transcript ID Kidney Liver
ENST00000253496 64.146±0.00 154.590±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0001 VISTA 5:177089375-177692188
CIL_0002YG CIL_0002YG_0001 CGP 5:177400107-177409576
CIL_0002YH CIL_0002YH_0001 CGP 5:177402140-177442901

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002353 IDA plasma kallikrein-kinin cascade
GO:0002542 IDA Factor XII activation
GO:0003824 IEA catalytic activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA:IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007596 TAS blood coagulation
GO:0007597 IC blood coagulation, intrinsic pathway
GO:0008233 IEA peptidase activity
GO:0010756 IDA positive regulation of plasminogen activation
GO:0016485 IDA protein processing
GO:0016540 IDA protein autoprocessing
GO:0030193 IEA regulation of blood coagulation
GO:0030194 IDA positive regulation of blood coagulation
GO:0031638 IDA zymogen activation
GO:0042730 IEA fibrinolysis
GO:0045087 TAS innate immune response
GO:0051787 IC misfolded protein binding
GO:0051788 IDA response to misfolded protein
GO:0051919 IDA positive regulation of fibrinolysis
GO:0070009 IEA serine-type aminopeptidase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021948 F12-001 protein_coding Mus_musculus 0 688

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