C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132855 ANGPTL3 9606 + 1:62597487-62606159 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371129 ANGPTL3-001 62597487-62606159 protein_coding
  ENST00000482591 ANGPTL3-002 62601034-62602380 processed_transcript
  ENST00000493994 ANGPTL3-003 62602320-62604658 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371129ENST00000482591ENST00000493994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371129 N/A 0.035±0.00 2.583±0.00 0.095±0.07 0.166±0.15 0.002±0.00 0.005±0.00 38.486±35.50 54.323±0.00 0.046±0.00 0.009±0.00 0.014±0.01 0.011±0.00 0.070±0.00
ENST00000482591 N/A 0.145±0.00 N/A 0.114±0.00 N/A 1.579±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000493994 0.101±0.00 0.024±0.00 N/A N/A N/A 0.693±0.64 0.332±0.00 N/A N/A N/A N/A 0.080±0.01 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002G2 CIL_0002G2_0001 CGP 1:62436297-62688368
CIL_000051 CIL_000051_0002 CGP 1:62454728-62688368
CIL_0002G5 CIL_0002G5_0001 CGP 1:62597487-62865513

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004857 ISS enzyme inhibitor activity
GO:0004859 IDA phospholipase inhibitor activity
GO:0005178 IPI integrin binding
GO:0005615 IDA extracellular space
GO:0006071 IDA glycerol metabolic process
GO:0006631 IDA fatty acid metabolic process
GO:0006644 IDA phospholipid metabolic process
GO:0007160 IPI cell-matrix adhesion
GO:0007165 IDA signal transduction
GO:0007229 NAS integrin-mediated signaling pathway
GO:0008083 IDA growth factor activity
GO:0008203 IDA cholesterol metabolic process
GO:0009395 IDA phospholipid catabolic process
GO:0009986 IDA cell surface
GO:0010519 IDA negative regulation of phospholipase activity
GO:0019915 IDA lipid storage
GO:0030335 IDA positive regulation of cell migration
GO:0042632 IDA cholesterol homeostasis
GO:0045766 IDA positive regulation of angiogenesis
GO:0048844 ISS artery morphogenesis
GO:0050996 IDA positive regulation of lipid catabolic process
GO:0051005 IDA negative regulation of lipoprotein lipase activity
GO:0055088 IDA lipid homeostasis
GO:0055090 IDA acylglycerol homeostasis
GO:0055091 IDA phospholipid homeostasis
GO:0070328 ISS triglyceride homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044365 angptl3 angiopoietin-like 3 protein_coding Danio_rerio
ENSMUSG00000028553 Angptl3 angiopoietin-like 3 protein_coding Mus_musculus

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