C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: doublecortin-like kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133083 DCLK1 9606 - 13:35768652-36131306 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255448 DCLK1-006 35771341-36131306 protein_coding
  ENST00000360631 DCLK1-010 35768963-36131306 protein_coding
  ENST00000379892 DCLK1-001 35849923-36131306 protein_coding
  ENST00000379893 DCLK1-011 35771339-35855642 protein_coding
  ENST00000460982 DCLK1-008 35845900-35855784 processed_transcript
  ENST00000477664 DCLK1-013 35787858-35793479 processed_transcript
  ENST00000486239 DCLK1-012 35805316-35808337 processed_transcript
  ENST00000615680 DCLK1-201 35768652-35855861 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255448ENST00000360631ENST00000379892ENST00000379893ENST00000460982ENST00000615680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255448 1.592±0.00 N/A 0.445±0.00 15.994±4.26 1.119±0.00 3.045±0.00 1.152±0.00 0.275±0.00 3.155±0.00 0.378±0.17 0.212±0.02 0.884±0.93 0.014±0.00 1.650±0.50
ENST00000360631 1.458±0.00 1.255±0.00 N/A 13.849±0.00 0.987±0.28 0.708±0.49 0.399±0.07 0.227±0.00 1.185±0.00 0.181±0.03 0.113±0.00 0.632±0.58 N/A 1.107±0.00
ENST00000379892 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.981±0.00 N/A N/A 0.012±0.00 N/A
ENST00000379893 1.931±0.00 1.816±0.00 N/A 27.760±6.03 2.086±0.70 1.317±0.00 0.800±0.00 N/A 0.008±0.00 0.277±0.00 0.182±0.00 1.320±0.70 0.113±0.05 1.391±0.00
ENST00000460982 N/A N/A N/A N/A N/A 0.735±0.28 0.852±0.00 0.199±0.16 0.659±0.64 0.697±0.00 N/A 0.262±0.24 0.022±0.02 2.229±0.00
ENST00000615680 N/A N/A N/A N/A N/A N/A N/A 0.060±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UJ CIL_0008UJ_0001 VISTA 13:35198777-35801835
CIL_0000P9 CIL_0000P9_0002 CGP 13:35474182-36131306

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005057 TAS receptor signaling protein activity
GO:0005524 IEA ATP binding
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007399 TAS nervous system development
GO:0007409 IEA axonogenesis
GO:0007417 TAS central nervous system development
GO:0007420 IEA brain development
GO:0009615 IEP response to virus
GO:0016197 NAS endosomal transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0021952 IEA central nervous system projection neuron axonogenesis
GO:0030900 IEA forebrain development
GO:0035556 IEA intracellular signal transduction
GO:0048675 IEA axon extension
GO:0048813 IEA dendrite morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018856 dclk1a doublecortin-like kinase 1a protein_coding Danio_rerio
ENSDARG00000074976 dckl1b doublecortin-like kinase 1b protein_coding Danio_rerio
ENSMUSG00000027797 Dclk1 doublecortin-like kinase 1 protein_coding Mus_musculus

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