C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134057 CCNB1 9606 + 5:69167010-69178245 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256442 CCNB1-001 69167010-69178245 protein_coding
  ENST00000503507 CCNB1-004 69167266-69174255 nonsense_mediated_decay
  ENST00000505500 CCNB1-002 69167263-69177630 protein_coding
  ENST00000506572 CCNB1-003 69167135-69177358 protein_coding
  ENST00000507798 CCNB1-006 69174257-69177700 protein_coding
  ENST00000508407 CCNB1-005 69167216-69175063 protein_coding
  ENST00000513102 CCNB1-007 69177061-69177697 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256442ENST00000503507ENST00000505500ENST00000506572ENST00000507798ENST00000508407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256442 N/A 0.276±0.00 N/A 0.699±0.23 0.874±0.48 1.448±0.96 0.087±0.01 0.833±0.00 0.065±0.00 0.690±0.00 0.102±0.00 2.698±1.25 3.129±1.55 2.732±1.10
ENST00000503507 N/A N/A N/A N/A N/A N/A 0.273±0.20 N/A N/A 0.333±0.00 N/A N/A N/A N/A
ENST00000505500 0.337±0.00 0.335±0.00 N/A N/A N/A N/A N/A 0.812±0.36 N/A 0.226±0.00 N/A N/A N/A N/A
ENST00000506572 0.706±0.00 0.698±0.00 0.406±0.00 1.599±0.04 3.230±0.83 5.134±4.11 0.309±0.06 0.729±0.35 0.501±0.00 0.546±0.00 0.225±0.20 9.236±6.67 10.039±3.45 14.615±0.09
ENST00000507798 N/A 0.397±0.00 N/A 1.410±0.59 1.240±0.00 1.570±0.00 0.638±0.00 1.033±0.00 0.412±0.00 N/A N/A 2.865±0.00 3.670±1.71 7.699±2.95
ENST00000508407 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.507±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000922 IDA spindle pole
GO:0000942 IDA condensed nuclear chromosome outer kinetochore
GO:0001556 IEA oocyte maturation
GO:0001701 IEA in utero embryonic development
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0005113 IPI patched binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0006461 IEA protein complex assembly
GO:0006468 IEA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007077 TAS mitotic nuclear envelope disassembly
GO:0007080 IMP mitotic metaphase plate congression
GO:0007283 IEA spermatogenesis
GO:0009612 IEA response to mechanical stimulus
GO:0009636 IEA response to toxic substance
GO:0010629 IEA negative regulation of gene expression
GO:0016020 IEA membrane
GO:0016301 IEA kinase activity
GO:0016572 IEA histone phosphorylation
GO:0019901 IPI:IEA protein kinase binding
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031442 IEA positive regulation of mRNA 3'-end processing
GO:0033129 IEA positive regulation of histone phosphorylation
GO:0035173 IEA histone kinase activity
GO:0042246 IEA tissue regeneration
GO:0042493 IEA response to drug
GO:0043148 IMP mitotic spindle stabilization
GO:0045787 IEA positive regulation of cell cycle
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0046680 IEA response to DDT
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048565 IEA digestive tract development
GO:0051301 IEA cell division
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051726 TAS:IEA regulation of cell cycle
GO:0051987 IMP positive regulation of attachment of spindle microtubules to kinetochore
GO:0055015 IEA ventricular cardiac muscle cell development
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060623 IEA regulation of chromosome condensation
GO:0071174 IMP mitotic spindle checkpoint
GO:0071283 IEA cellular response to iron(III) ion
GO:0071398 IEA cellular response to fatty acid
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071456 IEA cellular response to hypoxia
GO:2000775 IEA histone H3-S10 phosphorylation involved in chromosome condensation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051923 ccnb1 cyclin B1 protein_coding Danio_rerio
ENSDARG00000089062 ccnb1l cyclin B1, like protein_coding Danio_rerio
ENSMUSG00000041431 Ccnb1 cyclin B1 protein_coding Mus_musculus

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