C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041431 Ccnb1 10090 - 13:100778650-100786570 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072119 Ccnb1-001 100778650-100786570 protein_coding
  ENSMUST00000091295 Ccnb1-002 100778732-100786486 protein_coding
  ENSMUST00000128279 Ccnb1-005 100783044-100785603 retained_intron
  ENSMUST00000134080 Ccnb1-006 100779609-100782033 retained_intron
  ENSMUST00000142056 Ccnb1-004 100785537-100786475 retained_intron
  ENSMUST00000147790 Ccnb1-003 100778747-100781453 retained_intron
  ENSMUST00000174038 Ccnb1-007 100779678-100786402 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072119ENSMUST00000091295ENSMUST00000128279ENSMUST00000134080ENSMUST00000142056ENSMUST00000147790ENSMUST00000174038
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072119 1.083±0.86 0.189±0.10 1.130±0.04 11.233±0.49 0.318±0.25 1.360±0.85 0.112±0.01 0.108±0.05 58.730±27.68 0.165±0.01 0.098±0.00 3.099±1.76 20.040±20.39 8.093±2.61
ENSMUST00000091295 1.309±0.23 0.311±0.07 N/A N/A 0.757±0.07 1.732±0.61 N/A 0.206±0.09 5.400±9.17 0.451±0.10 0.048±0.04 4.944±1.95 0.212±0.00 N/A
ENSMUST00000128279 N/A N/A N/A 0.026±0.00 0.591±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000134080 1.443±0.98 0.653±0.41 N/A 0.027±0.00 0.378±0.12 3.884±1.20 N/A 0.315±0.10 0.124±0.05 0.507±0.11 0.213±0.00 6.828±2.24 N/A 9.095±1.92
ENSMUST00000142056 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.142±0.00 N/A N/A 20.681±0.00
ENSMUST00000147790 0.042±0.00 0.326±0.00 N/A 0.013±0.00 0.132±0.02 0.818±0.00 N/A 0.050±0.02 N/A N/A N/A N/A 0.128±0.00 N/A
ENSMUST00000174038 N/A N/A N/A N/A 0.312±0.00 N/A 0.053±0.00 N/A 0.103±0.00 0.277±0.00 0.033±0.00 N/A 11.082±10.18 7.551±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002SS CIL_0002SS_0002 CGP 13:100778650-100833427

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000278 IEA mitotic cell cycle
GO:0000922 IEA spindle pole
GO:0000942 IEA condensed nuclear chromosome outer kinetochore
GO:0001556 IEA oocyte maturation
GO:0001701 IMP in utero embryonic development
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0005113 IEA patched binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0006461 IEA protein complex assembly
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007080 IEA mitotic metaphase plate congression
GO:0007283 IEA spermatogenesis
GO:0009612 IEA response to mechanical stimulus
GO:0009636 IEA response to toxic substance
GO:0010629 IEA negative regulation of gene expression
GO:0016020 IDA membrane
GO:0016301 IDA kinase activity
GO:0016572 IEA histone phosphorylation
GO:0019901 IEA protein kinase binding
GO:0031442 IEA positive regulation of mRNA 3'-end processing
GO:0033129 IEA positive regulation of histone phosphorylation
GO:0035173 IEA histone kinase activity
GO:0042246 IEA tissue regeneration
GO:0042493 IEA response to drug
GO:0043148 IEA mitotic spindle stabilization
GO:0045787 IDA positive regulation of cell cycle
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046680 IEA response to DDT
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048565 IEA digestive tract development
GO:0051301 IEA cell division
GO:0051987 IEA positive regulation of attachment of spindle microtubules to kinetochore
GO:0055015 IEA ventricular cardiac muscle cell development
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060623 IEA regulation of chromosome condensation
GO:0071174 IEA mitotic spindle checkpoint
GO:0071283 IEA cellular response to iron(III) ion
GO:0071398 IEA cellular response to fatty acid
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071456 IEA cellular response to hypoxia
GO:2000775 IDA histone H3-S10 phosphorylation involved in chromosome condensation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051923 ccnb1 cyclin B1 protein_coding Danio_rerio
ENSDARG00000089062 ccnb1l cyclin B1, like protein_coding Danio_rerio
ENSG00000134057 CCNB1 cyclin B1 protein_coding Homo_sapiens

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