C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spexin hormone
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134548 SPX 9606 + 12:21526307-21537377 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256969 SPX-001 21526307-21532947 protein_coding
  ENST00000535033 SPX-005 21527044-21532523 retained_intron
  ENST00000535139 SPX-002 21527435-21532523 retained_intron
  ENST00000537527 SPX-007 21527952-21537377 processed_transcript
  ENST00000543800 SPX-003 21527936-21532523 processed_transcript
  ENST00000544637 SPX-006 21527301-21531524 processed_transcript
  ENST00000546199 SPX-004 21527131-21531485 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256969ENST00000535033ENST00000535139ENST00000543800ENST00000544637ENST00000546199
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256969 0.854±0.00 0.021±0.00 1.597±0.00 N/A 2.203±0.00 0.241±0.20 N/A N/A N/A N/A N/A 0.058±0.02 1.032±0.47 N/A
ENST00000535033 N/A N/A 1.089±0.00 2.074±0.00 N/A N/A N/A 5.468±0.00 0.500±0.00 N/A N/A N/A 1.702±0.89 N/A
ENST00000535139 1.424±0.00 N/A N/A 7.053±2.89 3.683±0.00 N/A 1.372±0.99 3.546±0.00 N/A 1.423±0.00 0.763±0.28 0.024±0.00 2.173±0.00 0.509±0.00
ENST00000543800 N/A 0.105±0.00 N/A 0.858±0.00 N/A 0.190±0.00 1.403±0.16 N/A N/A N/A N/A 0.062±0.03 N/A 0.506±0.00
ENST00000544637 N/A N/A N/A N/A 0.180±0.00 N/A N/A N/A N/A N/A N/A N/A 1.039±0.00 N/A
ENST00000546199 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.121±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XW CIL_0006XW_0002 CGP 12:21501781-21537377
CIL_0006XY CIL_0006XY_0002 CGP 12:21526307-21604847

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003084 ISS positive regulation of systemic arterial blood pressure
GO:0005179 IEA hormone activity
GO:0005184 IDA neuropeptide hormone activity
GO:0005615 IDA extracellular space
GO:0010459 ISS negative regulation of heart rate
GO:0031410 IEA cytoplasmic vesicle
GO:0031765 IDA type 2 galanin receptor binding
GO:0031766 IDA type 3 galanin receptor binding
GO:0032099 ISS negative regulation of appetite
GO:0035814 ISS negative regulation of renal sodium excretion
GO:0044539 ISS long-chain fatty acid import
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051930 ISS regulation of sensory perception of pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056859 SPX spexin hormone protein_coding Danio_rerio
ENSMUSG00000071112 B230216G23Rik RIKEN cDNA B230216G23 gene protein_coding Mus_musculus

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