C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: elongator acetyltransferase complex subunit 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134759 ELP2 9606 + 18:36129444-36180556 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000350494 ELP2-005 36129920-36174648 protein_coding
  ENST00000351393 ELP2-006 36129891-36174648 protein_coding
  ENST00000358232 ELP2-001 36129871-36180556 protein_coding
  ENST00000423854 ELP2-003 36129899-36174720 protein_coding
  ENST00000442325 ELP2-004 36129898-36174651 protein_coding
  ENST00000535093 ELP2-018 36141373-36146376 processed_transcript
  ENST00000535488 ELP2-012 36129902-36138641 retained_intron
  ENST00000536373 ELP2-017 36138807-36145358 retained_intron
  ENST00000536830 ELP2-023 36169936-36174745 retained_intron
  ENST00000539560 ELP2-002 36129901-36174721 nonsense_mediated_decay
  ENST00000540135 ELP2-013 36129903-36139760 processed_transcript
  ENST00000540323 ELP2-016 36138095-36142860 retained_intron
  ENST00000540730 ELP2-028 36137184-36142311 processed_transcript
  ENST00000540766 ELP2-021 36159758-36175032 nonsense_mediated_decay
  ENST00000540799 ELP2-015 36129925-36164485 nonsense_mediated_decay
  ENST00000541190 ELP2-010 36129894-36136632 retained_intron
  ENST00000541294 ELP2-022 36159957-36165225 retained_intron
  ENST00000541748 ELP2-026 36166966-36174653 retained_intron
  ENST00000542050 ELP2-019 36154931-36164667 processed_transcript
  ENST00000542430 ELP2-014 36129917-36142349 nonsense_mediated_decay
  ENST00000542824 ELP2-007 36129924-36174648 protein_coding
  ENST00000543127 ELP2-008 36129444-36142311 protein_coding
  ENST00000543439 ELP2-027 36137174-36142947 processed_transcript
  ENST00000543861 ELP2-020 36158503-36164620 processed_transcript
  ENST00000544267 ELP2-009 36129880-36141191 nonsense_mediated_decay
  ENST00000544274 ELP2-024 36170879-36174616 retained_intron
  ENST00000545302 ELP2-025 36166889-36174645 processed_transcript
  ENST00000545632 ELP2-011 36129895-36142857 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000351393ENST00000358232ENST00000423854ENST00000442325ENST00000535093ENST00000539560ENST00000540766ENST00000541748ENST00000544274
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000351393 6.362±0.00 9.170±0.00 N/A N/A 3.990±1.66 3.598±0.00 2.559±1.03 N/A N/A 2.728±0.01 6.844±0.00 8.099±2.11 5.731±0.87 5.715±0.00
ENST00000358232 N/A 3.842±0.00 1.089±0.00 N/A 2.854±0.00 N/A 1.364±0.00 N/A N/A 1.440±0.00 0.979±0.36 4.009±1.40 3.398±0.00 4.743±1.92
ENST00000423854 4.047±0.00 N/A N/A N/A N/A 4.573±0.00 N/A N/A 5.654±0.00 3.849±1.13 4.444±0.00 N/A 2.435±0.00 5.785±0.00
ENST00000442325 3.272±0.00 N/A N/A N/A 3.753±2.05 3.468±0.00 1.738±0.30 N/A 4.162±0.00 2.132±0.00 2.307±0.00 5.423±0.00 2.641±0.04 4.135±0.00
ENST00000535093 N/A N/A 8.884±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000539560 N/A N/A N/A 4.277±0.97 2.490±0.00 3.274±0.00 N/A 5.303±0.40 4.354±0.00 N/A N/A N/A N/A N/A
ENST00000540766 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.912±0.00 N/A N/A N/A
ENST00000541748 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 33.999±0.00 49.381±0.00 98.896±0.00
ENST00000544274 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.572±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000T CIL_00000T_0001 CGP 18:36108532-36180556
CIL_00000L CIL_00000L_0001 CGP 18:36129444-36272157

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0005515 IEA protein binding
GO:0005730 IC nucleolus
GO:0005737 IDA cytoplasm
GO:0006325 TAS chromatin organization
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006368 IC transcription elongation from RNA polymerase II promoter
GO:0008023 IDA transcription elongation factor complex
GO:0016591 IC DNA-directed RNA polymerase II, holoenzyme
GO:0019901 IEA protein kinase binding
GO:0033588 IDA Elongator holoenzyme complex
GO:0046425 IEA regulation of JAK-STAT cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017199 elp2 elongation protein 2 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000024271 Elp2 elongator acetyltransferase complex subunit 2 protein_coding Mus_musculus

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