C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135828 RNASEL 9606 - 1:182573634-182589256 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367559 RNASEL-001 182573634-182589256 protein_coding
  ENST00000539397 RNASEL-201 182578121-182589256 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367559ENST00000539397
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367559 2.018±0.00 0.711±0.00 1.230±0.00 0.930±0.22 1.856±0.32 2.161±0.66 0.585±0.20 2.164±1.82 1.797±1.18 1.526±0.28 0.388±0.04 2.598±1.15 3.121±0.35 1.297±0.65
ENST00000539397 N/A 0.542±0.00 N/A 0.231±0.04 0.713±0.44 0.487±0.00 0.135±0.00 N/A N/A 0.295±0.15 N/A 0.273±0.00 N/A 0.144±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IDA RNA binding
GO:0004521 NAS endoribonuclease activity
GO:0004540 IEA ribonuclease activity
GO:0004672 IEA protein kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006364 IEA rRNA processing
GO:0006397 IEA mRNA processing
GO:0006468 NAS:IEA protein phosphorylation
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016363 IEA nuclear matrix
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019843 IEA rRNA binding
GO:0045071 IDA negative regulation of viral genome replication
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051607 IDA defense response to virus
GO:0060337 TAS type I interferon signaling pathway
GO:0090502 NAS RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000066800 Rnasel ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) protein_coding Mus_musculus

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