C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: filamin B, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136068 FLNB 9606 + 3:58008400-58172251 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295956 FLNB-001 58008400-58172251 protein_coding
  ENST00000358537 FLNB-003 58008400-58172251 protein_coding
  ENST00000419752 FLNB-201 58168456-58172170 protein_coding
  ENST00000429972 FLNB-005 58008400-58172251 protein_coding
  ENST00000466455 FLNB-004 58149866-58153641 protein_coding
  ENST00000468939 FLNB-012 58154610-58159691 retained_intron
  ENST00000470231 FLNB-008 58149981-58153397 nonsense_mediated_decay
  ENST00000475487 FLNB-013 58156027-58163512 retained_intron
  ENST00000477629 FLNB-007 58149232-58151391 retained_intron
  ENST00000481470 FLNB-006 58132078-58172251 retained_intron
  ENST00000484981 FLNB-014 58165476-58170978 processed_transcript
  ENST00000490882 FLNB-002 58008400-58170774 protein_coding
  ENST00000491408 FLNB-011 58146678-58148364 retained_intron
  ENST00000493452 FLNB-009 58078329-58170777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295956ENST00000358537ENST00000419752ENST00000429972ENST00000481470ENST00000490882
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295956 27.330±0.00 13.829±0.00 N/A 0.614±0.00 6.954±3.34 15.775±2.80 2.249±1.89 8.948±2.10 4.356±1.26 10.065±2.74 1.977±0.00 13.094±5.99 22.006±4.95 9.371±0.00
ENST00000358537 N/A N/A N/A 2.839±1.52 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.719±0.00
ENST00000419752 25.990±0.00 33.985±0.00 N/A 7.124±0.00 18.521±0.00 16.450±0.00 8.997±0.00 33.457±0.00 13.604±0.00 13.532±0.00 1.518±0.00 29.940±17.91 23.144±0.00 18.764±9.61
ENST00000429972 N/A N/A 3.104±0.00 N/A 6.224±0.00 2.921±0.00 1.379±0.00 3.195±0.00 3.555±0.00 N/A N/A 2.577±0.55 6.824±2.42 N/A
ENST00000481470 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.740±0.00 N/A N/A
ENST00000490882 N/A N/A 3.709±0.00 N/A 2.693±0.00 6.029±0.00 N/A 3.374±0.00 5.447±0.00 N/A N/A 4.448±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UM CIL_0002UM_0001 CGP 3:58008400-58214697

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0003779 NAS actin binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007016 TAS cytoskeletal anchoring at plasma membrane
GO:0007165 TAS signal transduction
GO:0007519 IEA skeletal muscle tissue development
GO:0015629 TAS actin cytoskeleton
GO:0016021 NAS integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030036 TAS actin cytoskeleton organization
GO:0030154 IEA cell differentiation
GO:0042802 IPI identical protein binding
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000097351 flnbl filamin B, like protein_coding Danio_rerio
ENSMUSG00000025278 Flnb filamin, beta protein_coding Mus_musculus

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