C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136146 MED4 9606 - 13:48053323-48095131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258648 MED4-001 48075956-48095104 protein_coding
  ENST00000378586 MED4-002 48076968-48095131 protein_coding
  ENST00000417167 MED4-003 48077171-48095068 protein_coding
  ENST00000495013 MED4-005 48053323-48079975 non_stop_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258648ENST00000378586
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258648 4.926±0.00 7.485±0.00 0.261±0.00 3.642±1.48 3.396±2.55 3.969±1.86 5.102±0.00 2.990±2.02 2.306±1.05 2.001±1.32 1.974±1.76 5.868±3.64 7.596±2.39 9.163±4.51
ENST00000378586 6.244±0.00 10.766±0.00 N/A 3.635±2.83 3.757±2.23 3.092±2.32 5.330±0.00 8.478±0.00 2.062±0.13 4.321±0.00 5.116±0.00 16.461±8.43 10.023±1.69 16.547±2.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021H CIL_00021H_0002 CGP 13:48053323-48270357

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001104 IDA:IEA RNA polymerase II transcription cofactor activity
GO:0003712 IDA transcription cofactor activity
GO:0004872 IDA receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 IDA transcription initiation from RNA polymerase II promoter
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016592 IDA:IEA mediator complex
GO:0030374 NAS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030518 IDA intracellular steroid hormone receptor signaling pathway
GO:0030521 IDA androgen receptor signaling pathway
GO:0042809 NAS vitamin D receptor binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046966 IDA thyroid hormone receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041503 med4 mediator complex subunit 4 protein_coding Danio_rerio
ENSMUSG00000022109 Med4 mediator complex subunit 4 protein_coding Mus_musculus

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