C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycoprotein (transmembrane) nmb
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136235 GPNMB 9606 + 7:23235967-23275108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258733 GPNMB-001 23246563-23275108 protein_coding
  ENST00000381990 GPNMB-002 23246697-23275107 protein_coding
  ENST00000409458 GPNMB-007 23246709-23258048 protein_coding
  ENST00000459927 GPNMB-003 23246766-23253367 processed_transcript
  ENST00000463011 GPNMB-009 23273081-23274252 processed_transcript
  ENST00000465673 GPNMB-013 23235967-23260053 processed_transcript
  ENST00000468723 GPNMB-011 23273293-23274550 retained_intron
  ENST00000470994 GPNMB-012 23270043-23273925 processed_transcript
  ENST00000474157 GPNMB-004 23246774-23247367 processed_transcript
  ENST00000478451 GPNMB-010 23273269-23274729 processed_transcript
  ENST00000479625 GPNMB-008 23266140-23270175 retained_intron
  ENST00000487890 GPNMB-006 23246768-23256910 processed_transcript
  ENST00000492512 GPNMB-005 23250713-23254312 retained_intron
  ENST00000492858 GPNMB-014 23236008-23257043 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258733ENST00000381990ENST00000409458ENST00000468723ENST00000478451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258733 12.226±0.00 6.033±0.00 1.294±0.00 2.135±0.00 16.249±0.00 7.397±4.04 5.545±0.00 1.511±0.00 6.239±5.56 24.727±0.00 2.291±1.12 22.232±12.98 29.481±0.00 N/A
ENST00000381990 40.235±0.00 20.513±0.00 2.692±0.00 3.629±2.51 29.603±10.51 30.088±28.78 37.872±21.95 4.108±2.53 7.562±4.12 22.592±4.81 6.518±0.00 19.282±9.35 26.359±11.29 19.193±13.41
ENST00000409458 N/A N/A N/A 0.653±0.00 N/A N/A 2.965±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000468723 N/A N/A N/A 1.878±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000478451 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.947±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00059M CIL_00059M_0001 CGP 7:23235967-23311729

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0005178 IEA integrin binding
GO:0005887 IEA integral component of plasma membrane
GO:0007155 IEA cell adhesion
GO:0008201 IEA heparin binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0016021 TAS integral component of membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0030282 IEA bone mineralization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062688 gpnmb glycoprotein (transmembrane) nmb protein_coding Danio_rerio
ENSMUSG00000029816 Gpnmb glycoprotein (transmembrane) nmb protein_coding Mus_musculus

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