C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136378 ADAMTS7 9606 - 15:78759203-78811431 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000388820 ADAMTS7-001 78759203-78811431 protein_coding
  ENST00000565793 ADAMTS7-004 78770626-78800544 retained_intron
  ENST00000566303 ADAMTS7-002 78766833-78811283 processed_transcript
  ENST00000568712 ADAMTS7-003 78770795-78811232 retained_intron
  ENST00000569934 ADAMTS7-005 78763951-78765113 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000388820ENST00000565793ENST00000566303ENST00000568712
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000388820 2.081±0.00 1.140±0.00 N/A 1.047±0.00 0.184±0.17 1.587±1.34 0.167±0.00 0.067±0.00 1.343±0.00 0.114±0.00 2.362±0.56 3.510±2.11 1.395±0.52
ENST00000565793 N/A N/A 0.039±0.00 N/A 0.041±0.00 N/A N/A 0.102±0.00 0.749±0.00 N/A N/A N/A 0.579±0.00
ENST00000566303 N/A N/A 0.101±0.00 N/A N/A N/A N/A 0.168±0.04 N/A N/A N/A N/A N/A
ENST00000568712 N/A N/A N/A N/A N/A 0.120±0.00 0.113±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IDA:IEA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008233 IEA peptidase activity
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0009986 IEA cell surface
GO:0031012 IEA extracellular matrix
GO:0032331 IDA negative regulation of chondrocyte differentiation
GO:0051603 IMP proteolysis involved in cellular protein catabolic process
GO:0071347 IMP cellular response to interleukin-1
GO:0071356 IMP cellular response to tumor necrosis factor
GO:0071773 IDA cellular response to BMP stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000032363 Adamts7 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 protein_coding Mus_musculus

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