C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032363 Adamts7 10090 + 9:90163069-90208071 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000113059 Adamts7-001 90163069-90200100 protein_coding
  ENSMUST00000113060 Adamts7-003 90163226-90200102 protein_coding
  ENSMUST00000124441 Adamts7-004 90195128-90200097 retained_intron
  ENSMUST00000134996 Adamts7-002 90163124-90200100 nonsense_mediated_decay
  ENSMUST00000138227 Adamts7-006 90190984-90193487 processed_transcript
  ENSMUST00000144943 Adamts7-005 90188654-90191565 retained_intron
  ENSMUST00000147250 Adamts7-010 90163202-90199990 protein_coding
  ENSMUST00000167122 Adamts7-008 90163078-90208071 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000113059ENSMUST00000113060ENSMUST00000134996ENSMUST00000147250
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000113059 6.721±4.10 2.229±0.12 3.877±0.80 3.289±0.04 2.154±0.18 4.720±1.05 1.904±0.21 1.615±0.68 N/A 5.303±0.74 0.803±0.00 0.421±0.09
ENSMUST00000113060 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.17
ENSMUST00000134996 N/A N/A N/A N/A N/A 2.354±0.25 N/A N/A 0.250±0.00 N/A N/A N/A
ENSMUST00000147250 5.922±0.35 2.400±0.00 2.638±0.63 N/A N/A N/A N/A 1.978±0.42 N/A 3.995±0.00 0.831±0.20 0.780±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00085Y CIL_00085Y_0002 VISTA 9:90013787-90616367
CIL_0008X0 CIL_0008X0_0002 VISTA 9:90119621-90721316

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IDA proteolysis
GO:0008237 IDA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0032331 IEA negative regulation of chondrocyte differentiation
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071773 IEA cellular response to BMP stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000136378 ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 protein_coding Homo_sapiens

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