C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: iron-responsive element binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136381 IREB2 9606 + 15:78437431-78501456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258886 IREB2-001 78438189-78501456 protein_coding
  ENST00000558525 IREB2-008 78438228-78471801 nonsense_mediated_decay
  ENST00000558570 IREB2-003 78438309-78498209 nonsense_mediated_decay
  ENST00000559091 IREB2-009 78494210-78497338 protein_coding
  ENST00000559215 IREB2-006 78438176-78466436 nonsense_mediated_decay
  ENST00000559427 IREB2-007 78465299-78470948 processed_transcript
  ENST00000559676 IREB2-010 78483420-78488756 retained_intron
  ENST00000560440 IREB2-002 78438284-78476700 protein_coding
  ENST00000560454 IREB2-005 78438422-78462944 processed_transcript
  ENST00000560840 IREB2-004 78437431-78465264 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258886ENST00000558570
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258886 3.876±0.00 3.490±0.00 2.398±0.00 4.671±0.96 5.699±0.00 4.621±1.81 3.089±1.03 4.557±0.80 3.362±1.45 4.522±1.54 3.285±0.00 4.065±1.22 4.514±1.11 7.457±0.14
ENST00000558570 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.510±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00020I CIL_00020I_0001 CGP 15:78340324-78501456
CIL_0001UQ CIL_0001UQ_0001 CGP 15:78437431-78537372

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IDA RNA binding
GO:0005515 IPI protein binding
GO:0005737 NAS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0006417 IEA regulation of translation
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006826 IEA:TAS iron ion transport
GO:0006879 IEA cellular iron ion homeostasis
GO:0007568 IEA aging
GO:0008152 IEA metabolic process
GO:0009791 IEA post-embryonic development
GO:0010040 IEA response to iron(II) ion
GO:0010468 IEA regulation of gene expression
GO:0017148 IEA negative regulation of translation
GO:0030316 IEA osteoclast differentiation
GO:0030350 TAS iron-responsive element binding
GO:0030371 IEA translation repressor activity
GO:0032526 IEA response to retinoic acid
GO:0034101 IEA erythrocyte homeostasis
GO:0046872 IEA metal ion binding
GO:0050892 IEA intestinal absorption
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055072 IEA iron ion homeostasis
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021466 ireb2 iron-responsive element binding protein 2 protein_coding Danio_rerio
ENSMUSG00000032293 Ireb2 iron responsive element binding protein 2 protein_coding Mus_musculus

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