C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 receptor antagonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136689 IL1RN 9606 + 2:113107214-113134016 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259206 IL1RN-001 113117897-113134016 protein_coding
  ENST00000354115 IL1RN-002 113117897-113134016 protein_coding
  ENST00000361779 IL1RN-003 113117893-113134016 protein_coding
  ENST00000409052 IL1RN-004 113111116-113134013 protein_coding
  ENST00000409930 IL1RN-005 113127561-113133121 protein_coding
  ENST00000463073 IL1RN-006 113111116-113115690 processed_transcript
  ENST00000465812 IL1RN-007 113107214-113117665 processed_transcript
  ENST00000472292 IL1RN-009 113127576-113129982 retained_intron
  ENST00000486167 IL1RN-008 113117981-113130121 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259206ENST00000354115ENST00000361779ENST00000409052ENST00000409930ENST00000486167
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259206 0.321±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000354115 N/A 0.261±0.00 0.070±0.00 9.248±0.00 0.965±0.00 0.716±0.00 6.256±0.00 8.607±0.00 N/A 14.201±13.51 1.364±0.61 1.312±0.00
ENST00000361779 0.261±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.183±0.00 0.226±0.00 N/A
ENST00000409052 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.814±0.00
ENST00000409930 N/A N/A N/A 0.308±0.00 N/A N/A 0.369±0.00 0.680±0.00 1.139±0.00 N/A N/A N/A
ENST00000486167 N/A N/A N/A N/A N/A N/A N/A 1.506±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000190 CIL_000190_0001 CGP 2:113067970-113134016
CIL_000191 CIL_000191_0001 CGP 2:113107214-113209396

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0001960 IDA negative regulation of cytokine-mediated signaling pathway
GO:0002439 IEA chronic inflammatory response to antigenic stimulus
GO:0005149 IDA interleukin-1 receptor binding
GO:0005150 IPI interleukin-1, Type I receptor binding
GO:0005151 IPI interleukin-1, Type II receptor binding
GO:0005152 IDA interleukin-1 receptor antagonist activity
GO:0005576 IEA extracellular region
GO:0005615 IDA:IEA extracellular space
GO:0005622 NAS intracellular
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006953 IDA acute-phase response
GO:0006955 NAS immune response
GO:0007565 IEA female pregnancy
GO:0007613 IEA memory
GO:0010243 IEA response to organonitrogen compound
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0019233 IEA sensory perception of pain
GO:0019752 IEA carboxylic acid metabolic process
GO:0030073 IEA insulin secretion
GO:0030336 IEA negative regulation of cell migration
GO:0031982 IEA vesicle
GO:0032496 IEA response to lipopolysaccharide
GO:0034115 IDA negative regulation of heterotypic cell-cell adhesion
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045352 IDA interleukin-1 Type I receptor antagonist activity
GO:0045353 IDA interleukin-1 Type II receptor antagonist activity
GO:0045837 IEA negative regulation of membrane potential
GO:0051384 IDA response to glucocorticoid
GO:0070062 IDA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0070670 IEA response to interleukin-4
GO:0071874 IEA cellular response to norepinephrine stimulus
GO:2000660 IDA negative regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026981 Il1rn interleukin 1 receptor antagonist protein_coding Mus_musculus

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