C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 receptor antagonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026981 Il1rn 10090 + 2:24336853-24351494 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114482 Il1rn-002 24345310-24350936 protein_coding
  ENSMUST00000114485 Il1rn-005 24345288-24349807 protein_coding
  ENSMUST00000114486 Il1rn-003 24337736-24349633 protein_coding
  ENSMUST00000114487 Il1rn-001 24336853-24351494 protein_coding
  ENSMUST00000142093 Il1rn-004 24336856-24349457 processed_transcript
  ENSMUST00000143423 Il1rn-006 24345348-24346354 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114482ENSMUST00000114485ENSMUST00000114486ENSMUST00000114487ENSMUST00000142093ENSMUST00000143423
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114482 0.754±0.37 0.071±0.03 1.173±0.01 0.033±0.02 0.870±0.32 13.831±3.61 0.062±0.06 0.150±0.10 2.915±2.72 5.472±1.52 0.058±0.03 0.693±0.33 1.095±0.93 N/A
ENSMUST00000114485 0.463±0.00 N/A N/A N/A 0.270±0.00 5.654±0.00 0.049±0.00 0.076±0.03 1.207±0.62 N/A N/A 0.649±0.00 1.092±0.30 0.047±0.00
ENSMUST00000114486 N/A N/A N/A N/A N/A N/A 0.051±0.00 N/A N/A N/A N/A 0.907±0.44 N/A 0.143±0.05
ENSMUST00000114487 0.171±0.11 N/A 0.666±0.33 N/A 0.234±0.00 2.759±0.34 N/A N/A 0.839±0.48 1.064±0.00 N/A 0.141±0.05 0.252±0.07 N/A
ENSMUST00000142093 N/A N/A N/A N/A N/A N/A N/A 0.198±0.00 N/A N/A N/A 1.157±0.00 N/A N/A
ENSMUST00000143423 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.097±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000190 CIL_000190_0002 CGP 2:24291196-24351494
CIL_000191 CIL_000191_0002 CGP 2:24336853-24409182

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0001960 IEA negative regulation of cytokine-mediated signaling pathway
GO:0002439 IEA chronic inflammatory response to antigenic stimulus
GO:0005149 IEA interleukin-1 receptor binding
GO:0005150 IEA interleukin-1, Type I receptor binding
GO:0005151 IEA interleukin-1, Type II receptor binding
GO:0005152 IEA interleukin-1 receptor antagonist activity
GO:0005576 IDA extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006629 IMP lipid metabolic process
GO:0006953 IEA acute-phase response
GO:0007565 IEA female pregnancy
GO:0007613 IEA memory
GO:0010243 IEA response to organonitrogen compound
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0019233 IEA sensory perception of pain
GO:0019752 IEA carboxylic acid metabolic process
GO:0030073 IMP insulin secretion
GO:0030336 IEA negative regulation of cell migration
GO:0031982 IDA vesicle
GO:0032496 IEA response to lipopolysaccharide
GO:0034115 IEA negative regulation of heterotypic cell-cell adhesion
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045352 IEA interleukin-1 Type I receptor antagonist activity
GO:0045353 IEA interleukin-1 Type II receptor antagonist activity
GO:0045837 IEA negative regulation of membrane potential
GO:0051384 IEA response to glucocorticoid
GO:0070062 IEA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0070670 IEA response to interleukin-4
GO:0071874 IEA cellular response to norepinephrine stimulus
GO:2000660 IEA negative regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000136689 IL1RN interleukin 1 receptor antagonist protein_coding Homo_sapiens

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