C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: syntaxin binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136854 STXBP1 9606 + 9:127612265-127692716 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373299 STXBP1-002 127612289-127692716 protein_coding
  ENST00000373302 STXBP1-001 127612265-127692716 protein_coding
  ENST00000476182 STXBP1-006 127612411-127613476 processed_transcript
  ENST00000494254 STXBP1-005 127678524-127684666 protein_coding
  ENST00000496504 STXBP1-003 127661164-127663722 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373299ENST00000373302
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373299 18.625±0.00 9.644±0.00 0.640±0.00 61.786±52.82 8.486±6.22 9.651±9.03 3.720±3.44 4.807±4.46 1.135±0.15 18.074±16.52 3.256±0.00 17.450±10.98 9.216±1.37 12.266±2.66
ENST00000373302 N/A N/A N/A 40.171±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YA CIL_0008YA_0001 VISTA 9:127227593-127829012
CIL_0002C5 CIL_0002C5_0003 CGP 9:127505339-127692716

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000149 ISS SNARE binding
GO:0002576 IMP platelet degranulation
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006887 IEA exocytosis
GO:0006904 IEA vesicle docking involved in exocytosis
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007412 ISS axon target recognition
GO:0010807 ISS regulation of synaptic vesicle priming
GO:0014047 TAS glutamate secretion
GO:0015031 IEA protein transport
GO:0016188 ISS synaptic vesicle maturation
GO:0016192 IEA vesicle-mediated transport
GO:0017075 ISS syntaxin-1 binding
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0019905 IPI syntaxin binding
GO:0031091 IDA platelet alpha granule
GO:0031630 TAS regulation of synaptic vesicle fusion to presynaptic membrane
GO:0032229 ISS negative regulation of synaptic transmission, GABAergic
GO:0035542 TAS regulation of SNARE complex assembly
GO:0042802 ISS identical protein binding
GO:0043234 ISS protein complex
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045921 IEA positive regulation of exocytosis
GO:0045956 IEA positive regulation of calcium ion-dependent exocytosis
GO:0047485 IEA protein N-terminus binding
GO:0050796 TAS regulation of insulin secretion
GO:0050821 IEA protein stabilization
GO:0060292 IEA long term synaptic depression
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IMP platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001994 stxbp1a syntaxin binding protein 1a protein_coding Danio_rerio
ENSDARG00000056036 stxbp1b syntaxin binding protein 1b protein_coding Danio_rerio
ENSDARG00000088599 stxbp1b syntaxin binding protein 1b protein_coding Danio_rerio
ENSMUSG00000026797 Stxbp1 syntaxin binding protein 1 protein_coding Mus_musculus

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