C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) B receptor, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136928 GABBR2 9606 - 9:98288109-98709197 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259455 GABBR2-001 98288109-98709197 protein_coding
  ENST00000477471 GABBR2-002 98473230-98555898 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259455ENST00000477471
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259455 0.684±0.00 0.013±0.00 15.127±10.00 0.017±0.00 0.015±0.00 0.203±0.19 0.019±0.00 0.045±0.03 0.031±0.00 0.014±0.00 0.023±0.02 0.060±0.03 0.179±0.00
ENST00000477471 N/A N/A N/A N/A N/A N/A 0.059±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00029Z CIL_00029Z_0001 CGP 9:98198999-98709197
CIL_000202 CIL_000202_0001 CGP 9:98288109-98796965

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004965 IDA G-protein coupled GABA receptor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007194 TAS negative regulation of adenylate cyclase activity
GO:0007214 IDA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0038039 IPI G-protein coupled receptor heterodimeric complex
GO:0043005 IEA neuron projection
GO:0045211 IEA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061042 gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 protein_coding Danio_rerio
ENSMUSG00000039809 Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 protein_coding Mus_musculus

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