C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, beta type, 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136930 PSMB7 9606 - 9:124353466-124415444 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259457 PSMB7-001 124353466-124415439 protein_coding
  ENST00000441097 PSMB7-003 124396760-124415444 protein_coding
  ENST00000466951 PSMB7-006 124412400-124415307 processed_transcript
  ENST00000474081 PSMB7-004 124383596-124384656 processed_transcript
  ENST00000478817 PSMB7-005 124383622-124384656 processed_transcript
  ENST00000498485 PSMB7-002 124353466-124415291 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259457ENST00000441097
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259457 63.074±0.00 67.857±0.00 6.303±0.00 54.642±16.21 37.983±30.11 35.531±18.85 37.310±22.19 56.385±21.36 50.600±32.94 29.467±19.45 45.764±16.87 58.374±26.72 97.030±36.32 81.660±33.93
ENST00000441097 N/A N/A N/A N/A 4.910±0.00 N/A 4.462±0.00 N/A N/A N/A N/A 15.783±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MV CIL_0007MV_0001 UCNEbase 9:123742251-124385977
CIL_0008N3 CIL_0008N3_0001 VISTA 9:123985007-124587009
CIL_00098L CIL_00098L_0001 VISTA 9:124060941-124661966
CIL_0006WG CIL_0006WG_0001 CGP 9:124257606-124415444

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0015630 IDA microtubule cytoskeleton
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037962 psmb7 proteasome (prosome, macropain) subunit, beta type, 7 protein_coding Danio_rerio
ENSMUSG00000026750 Psmb7 proteasome (prosome, macropain) subunit, beta type 7 protein_coding Mus_musculus

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