C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: derlin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136986 DERL1 9606 - 8:123013164-123042423 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259512 DERL1-001 123013164-123042423 protein_coding
  ENST00000405944 DERL1-004 123014149-123042122 protein_coding
  ENST00000419562 DERL1-002 123015165-123042302 protein_coding
  ENST00000519018 DERL1-006 123015442-123025650 protein_coding
  ENST00000523036 DERL1-005 123015446-123025772 protein_coding
  ENST00000524119 DERL1-003 123014149-123030719 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259512ENST00000405944ENST00000524119
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259512 N/A 27.532±0.00 N/A 3.107±0.00 N/A 5.337±3.29 1.926±0.00 9.745±6.79 2.615±0.00 N/A N/A 6.656±3.81 4.204±1.87 7.254±0.00
ENST00000405944 18.272±0.00 N/A 2.407±0.00 5.465±1.76 12.093±0.08 5.456±0.78 7.015±3.15 8.743±2.04 11.435±2.58 9.296±3.26 10.819±3.48 12.238±6.10 11.421±5.72 12.288±4.05
ENST00000524119 N/A N/A 0.925±0.00 N/A N/A N/A N/A 1.015±0.00 N/A 1.622±0.00 N/A 1.580±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BI CIL_0000BI_0002 CGP 8:122781394-123042423
CIL_0005HY CIL_0005HY_0001 CGP 8:123013164-123152153

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000836 IDA Hrd1p ubiquitin ligase complex
GO:0004872 NAS receptor activity
GO:0005515 IPI protein binding
GO:0005769 IEA early endosome
GO:0005770 IEA late endosome
GO:0005783 IDA endoplasmic reticulum
GO:0006986 IMP response to unfolded protein
GO:0016020 IDA membrane
GO:0016021 IDA integral component of membrane
GO:0019060 TAS intracellular transport of viral protein in host cell
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030433 IDA ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0030970 IMP retrograde protein transport, ER to cytosol
GO:0034620 IEA cellular response to unfolded protein
GO:0042288 IDA MHC class I protein binding
GO:0045184 TAS establishment of protein localization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021905 derl1 Der1-like domain family, member 1 protein_coding Danio_rerio
ENSMUSG00000022365 Derl1 Der1-like domain family, member 1 protein_coding Mus_musculus

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