C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: talin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137076 TLN1 9606 - 9:35696948-35732395 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314888 TLN1-001 35696948-35732395 protein_coding
  ENST00000378192 TLN1-002 35723104-35732104 retained_intron
  ENST00000464379 TLN1-005 35703559-35707874 processed_transcript
  ENST00000465002 TLN1-007 35703783-35704415 retained_intron
  ENST00000466916 TLN1-008 35703560-35704193 retained_intron
  ENST00000486788 TLN1-006 35704323-35706198 retained_intron
  ENST00000489255 TLN1-003 35698044-35699328 processed_transcript
  ENST00000495712 TLN1-004 35707356-35707967 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314888ENST00000378192
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314888 39.548±0.00 86.688±0.00 8.873±0.00 5.792±2.88 61.657±44.14 52.245±42.32 12.970±7.91 23.661±17.76 20.626±6.95 19.520±6.83 54.909±0.00 42.743±36.30 52.873±2.01 22.699±5.94
ENST00000378192 N/A N/A 23.127±0.00 N/A N/A 24.754±0.00 9.830±0.00 N/A 54.998±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BX CIL_0007BX_0001 CGP 9:35681992-35732395
CIL_0007C0 CIL_0007C0_0001 CGP 9:35696948-35737007

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS:IEA ruffle
GO:0002576 TAS platelet degranulation
GO:0003779 IEA actin binding
GO:0005158 IEA insulin receptor binding
GO:0005178 IPI integrin binding
GO:0005200 NAS:IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005737 IDA cytoplasm
GO:0005815 IDA microtubule organizing center
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005911 IC cell-cell junction
GO:0005925 ISS:IEA focal adhesion
GO:0006928 NAS cellular component movement
GO:0006936 TAS muscle contraction
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007016 NAS:IEA cytoskeletal anchoring at plasma membrane
GO:0007043 TAS cell-cell junction assembly
GO:0007044 IEA cell-substrate junction assembly
GO:0007155 IEA cell adhesion
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0015629 IEA actin cytoskeleton
GO:0017166 IPI vinculin binding
GO:0030168 TAS platelet activation
GO:0030274 IPI LIM domain binding
GO:0030866 IEA cortical actin cytoskeleton organization
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0032403 IEA protein complex binding
GO:0044267 TAS cellular protein metabolic process
GO:0051015 IEA actin filament binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IMP platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005333 tln1 talin 1 protein_coding Danio_rerio
ENSMUSG00000028465 Tln1 talin 1 protein_coding Mus_musculus

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