C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: talin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028465 Tln1 10090 - 4:43531519-43562691 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030187 Tln1-001 43531519-43562422 protein_coding
  ENSMUST00000123985 Tln1-002 43559343-43562691 processed_transcript
  ENSMUST00000125509 Tln1-006 43546822-43551271 protein_coding
  ENSMUST00000126078 Tln1-005 43555564-43555946 processed_transcript
  ENSMUST00000127262 Tln1-008 43553451-43554451 processed_transcript
  ENSMUST00000130353 Tln1-004 43555106-43558460 protein_coding
  ENSMUST00000130670 Tln1-003 43554514-43562157 processed_transcript
  ENSMUST00000134623 Tln1-007 43545410-43547647 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030187
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030187 49.602±8.73 88.311±24.81 41.207±4.20 10.989±0.87 66.377±14.09 47.410±8.57 22.732±2.93 36.875±10.09 15.711±7.36 96.162±16.84 7.869±2.42 81.182±32.85 52.568±26.06 7.621±0.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BX CIL_0007BX_0002 CGP 4:43514711-43562691
CIL_0007C0 CIL_0007C0_0002 CGP 4:43531519-43567060

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0003779 IEA actin binding
GO:0005158 IEA insulin receptor binding
GO:0005178 IEA integrin binding
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005815 IEA microtubule organizing center
GO:0005886 IEA plasma membrane
GO:0005925 IDA:ISS focal adhesion
GO:0007016 IEA cytoskeletal anchoring at plasma membrane
GO:0007044 IMP cell-substrate junction assembly
GO:0007155 IEA cell adhesion
GO:0015629 IEA actin cytoskeleton
GO:0017166 IEA vinculin binding
GO:0030274 IEA LIM domain binding
GO:0030866 IMP cortical actin cytoskeleton organization
GO:0032403 IEA protein complex binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005333 tln1 talin 1 protein_coding Danio_rerio
ENSG00000137076 TLN1 talin 1 protein_coding Homo_sapiens

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